Variables | Univariable | Multivariable$, n = 226 | ||
---|---|---|---|---|
OR | p | OR | p | |
HAQ, 3rd trimester ≥ 0.75 | 3.121+ | < 0.001+ | 3.669* | < 0.001* |
Autoantibody status–positive | 2.649+ | 0.002+ | 3.210* | 0.003* |
Smoking% | 3.841+ | 0.075+ | 5.902* | 0.032* |
MTX use in past | 1.857+ | 0.034+ | 1.659 | 0.143 |
SES based on educational level | 0.696+ | 0.156+ | 0.661 | 0.150 |
Prednisone use, 3rd trimester | 3.378+ | 0.001+ | 1.924 | 0.114 |
Presence of erosions | 1.693+ | 0.071+ | – | – |
DAS28-CRP3 3rd trimester | 1.305+ | 0.052+ | – | – |
SSZ use, 3rd trimester | 0.991 | 0.980 | ||
VAS global health | 0.999 | 0.474 | ||
Maternal age | 0.989 | 0.774 | ||
Parity ≥ 1 | 1.106 | 0.737 |
↵# Based on logistic regression.
↵$ Multivariable model after forward selection (limit for inclusion: p < 0.20) and backward selection (limit for exclusion: p ≥ 0.20).
↵% Smoking periconceptionally or during pregnancy.
↵+ Variables taken forward if p < 0.20.
↵* Statistically significant in the multivariable model. HAQ: Health Assessment Questionnaire; MTX: methotrexate; SES: socioeconomic status; DAS28-CRP3: 28-joint Disease Activity Score using C-reactive protein levels; VAS: visual analog scale; SSZ: sulfasalazine.