Table 2.

Baseline status (median, interquartile range) and change scores (median, range) of each MRI feature for the CMC-1 and STT joints in 2 reliability exercises. Based on average score of all readers, except subluxation^†. Separate scores for the distal and proximal part of the joint combined into sum score per joint.

MRI Feature, Range CMC-1/STT	HOSTAS Cohort, n = 25				Clinical Trial, n = 24
	CMC-1		STT		CMC-1		STT^*
	Baseline	Change, 2 Yrs	Baseline	Change, 2 Yrs	Baseline	Change, 6 Mos	Baseline	Change, 6 Mos
Synovitis, 0–3/0–3	1.3 (0.7–1.7)	0 (−1.7 to 1)	0.7 (0.3–1.3)	0 (−0.7 to 1)	1.5 (1–2)	0 (−1 to 1)	0.5 (0–1)	0 (0–0.5)
Subchondral bone defects, 0–6/0–9	1.7 (0.7–2.3)	0.2 (−0.7 to 2.2)	0.7 (0–1.7)	0 (−0.2 to 2.3)
Osteophytes, 0–6/0–9	2.3 (1.7–4)	0 (0–0.7)	0.7 (0.3–1)	0 (0–0.3)
Cartilage assessment, 0–3/0–3	1 (0.7–1.7)	0 (−0.3 to 0.7)	0.7 (0–1.3)	0 (−1.7 to 1)
Subluxation, absent or present	8 (32%)^†	0 (0 –0.3)
Bone marrow lesions, 0–6/0–9	1.7 (0.7–4.3)	0 (−3.2 to 4.7)	1 (0.3–2.3)	0 (−2.7 to 3)	1.3 (0.5–2.5)	0 (−5 to 4)	0 (0–1.3)	0 (−2.5 to 3)

↵* STT scored in 16 patients, trapezoid not included.
↵† n (%) with subluxation scored by at least 2 readers. MRI: magnetic resonance imaging; CMC-1: first carpometacarpal joint; STT: scaphotrapeziotrapezoid joint; HOSTAS: Hand Osteoarthritis in Secondary Care.