Table 3.

Clinical and demographic features of CLAAS cohort.

FeaturesN (%)
Clinical features
  Hematologic (any)46 (92)
    Anemia42 (84)
    Leukopenia33 (66)
    Neutropenia23 (46)
  Renal39 (78)
  Dermatologic (any)29 (58)
    Purpura/ulcers21 (42)
  MSK20 (40)
  ENT5 (10)
  Pulmonary2 (4)
Laboratory features
  Antiphospholipid antibody (any)19/28 (68)
    Anticardiolipin IgM18/28 (64)
    Anticardiolipin IgG5/28 (18)
    Anti-β2 glycoprotein IgM9/24 (38)
    Anti-β2 glycoprotein IgG3/28 (11)
  Lupus inhibitor15/19 (79)
  Evidence of HCV exposure32/48 (67)
    HCV viremia23/49 (47)
  Evidence of HIV infection3/47 (6)
  Low C3 or C415/33 (45)
  Cryoglobulinemia8/28 (29)
  RF8/33 (24)
  ANA11/48 (23)
  Levamisole detected in urine14/36 (39)
  • CLAAS: cocaine/levamisole-associated autoimmunity syndrome; MSK: musculoskeletal; HCV: hepatitis C virus; HIV: human immunodeficiency virus; RF: rheumatoid factor; ANA: antinuclear antibody; IgM: immunoglobulin M.