Features | N (%) |
---|---|
Clinical features | |
Hematologic (any) | 46 (92) |
Anemia | 42 (84) |
Leukopenia | 33 (66) |
Neutropenia | 23 (46) |
Renal | 39 (78) |
Dermatologic (any) | 29 (58) |
Purpura/ulcers | 21 (42) |
MSK | 20 (40) |
ENT | 5 (10) |
Pulmonary | 2 (4) |
Laboratory features | |
Antiphospholipid antibody (any) | 19/28 (68) |
Anticardiolipin IgM | 18/28 (64) |
Anticardiolipin IgG | 5/28 (18) |
Anti-β2 glycoprotein IgM | 9/24 (38) |
Anti-β2 glycoprotein IgG | 3/28 (11) |
Lupus inhibitor | 15/19 (79) |
Evidence of HCV exposure | 32/48 (67) |
HCV viremia | 23/49 (47) |
Evidence of HIV infection | 3/47 (6) |
Low C3 or C4 | 15/33 (45) |
Cryoglobulinemia | 8/28 (29) |
RF | 8/33 (24) |
ANA | 11/48 (23) |
Levamisole detected in urine | 14/36 (39) |
CLAAS: cocaine/levamisole-associated autoimmunity syndrome; MSK: musculoskeletal; HCV: hepatitis C virus; HIV: human immunodeficiency virus; RF: rheumatoid factor; ANA: antinuclear antibody; IgM: immunoglobulin M.