Scores | DAS28 | TJC28 | SJC28 | PtGA | PGA | CRP | ESR* | PFTS*£ | USPD* | USBM* |
---|---|---|---|---|---|---|---|---|---|---|
Inflammation scores | ||||||||||
1. Unweighted summation | 0.32 | 0.14 | 0.42 | 0.12 | 0.32 | 0.40 | 0.24 | −0.26 | 0.49 | 0.54 |
2. Normalized summation | 0.36 | 0.18 | 0.46 | 0.14 | 0.35 | 0.43 | 0.24 | −0.25 | 0.52 | 0.55 |
3. Weighted summation | 0.27 | 0.13 | 0.38 | 0.11 | 0.29 | 0.33 | 0.17 | −0.29 | 0.47 | 0.52 |
4. Adjusted-weighted summation | 0.30 | 0.15 | 0.42 | 0.11 | 0.31 | 0.37 | 0.19 | −0.28 | 0.50 | 0.54 |
5. Single site–weighted summation | 0.29 | 0.14 | 0.36 | 0.11 | 0.29 | 0.32 | 0.21 | −0.26 | 0.46 | 0.48 |
Damage scores | CR Erosions | CR JSN | CR Total | |||||||
1. Unweighted summation | 0.43 | 0.33 | 0.40 | |||||||
2. Normalized summation | 0.41 | 0.32 | 0.38 | |||||||
3. Weighted summation | 0.43 | 0.34 | 0.40 | |||||||
4. Adjusted-weighted summation | 0.43 | 0.33 | 0.40 | |||||||
5. Single site–weighted summation | 0.42 | 0.37 | 0.43 |
↵* ARCTIC trial only.
↵£ Negative correlation because of inverse scale of PROMIS T score. All coefficients significant at the 0.05 level. CR: conventional radiography [CR scored by modified Sharp/van der Heijde score (hands, wrists, and feet)]; CRP: C-reactive protein (mg/l); DAS28: 28-joint count Disease Activity Score (range 0–10); ESR: erythrocyte sedimentation rate; MRI: magnetic resonance imaging; PtGA/PGA: patient’s/physician’s global assessment visual analog scale (range 0–100); PFTS: PROMIS T score; PROMIS: Patient Reported Outcomes Measurement Information System; SJC: swollen joint count in 28 joints; TJC: tender joint count in 28 joints; USPD/USBM: ultrasound power-Doppler/B-mode.