Metric properties of VAS and NRS measuring pain and patient’s global assessment (PtGA): construct validity, reliability, longitudinal construct validity (responsiveness), and clinical trial discrimination.
| Domain | Scale | Construct Validity | Reliability | Longitudinal Construct Validity (Responsiveness) | Clinical Trial Discrimination | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Studies Showing Significant Correlation with: | No. Studies | No. Studies Showing Change | No. Studies Showing no Change, in Disagreement with Other Outcomes | Percentage of Studies That Detected Change | No. Studies Showing Discrimination Between Arms in Agreement with Primary Outcome | No. Studies Not Showing Discrimination Between Arms in Agreement with Primary Outcome | No. Studies Showing Discrimination Between Arms in Disagreement with Primary Outcome | No. Studies Not Showing Discrimination Between Arms in Disagreement with Primary Outcome | ||
| Pain | VAS | AUSCAN pain: r = 0.77–0.81 (S3, S24, S50) | 0 | 22 (S1, S2, S4, S6–S13, S15–S18, S21, S22, S26, S37, S38, S42, S46)# | 3 (S31, S39, S44) | 88 | 13 (S7–S12, S17, S21, S22, S26, S37, S38, S46) | 6 (S1, S5, S6, S23, S32, S44) | 2 (S13, S42) | 7 (S15, S19, S30, S39, S43, S48, S49) |
| NRS | AUSCAN pain: R2 = 0.606 (S41) AUSCAN function: R2 = 0.471 (S41) | 0 | 8 (S15, S25, S28, S33, S34, S41, S45, S47) | 0 | 100 | 6 (S14, S28, S33, S34, S41, S47) | 0 | 1 (S16) | 1 (S25) | |
| PtGA | VAS | 0 | 0 | 10 (S3, S6, S12, S13, S15, S18, S22, S29, S38, S40)# | 0 | 100 | 5 (S12, S22, S29, S38, S40) | 2 (S6, S40) | 1 (S15) | 0 |
| NRS | 0 | 0 | 3 (S14, S28, S45) | 0 | 100 | 1 [S28] | 0 | 0 | 1 (S14) | |
↵# Saviola, et al (S38): no hard data shown, only described in full text. S(number): refers to the reference in the Supplementary Reference list (available with the online version of this article). VAS: visual analog scale; NRS: numerical rating scale; AUSCAN: Australian/Canadian Hand OA Index; r: coefficient of correlation; R2: correlation.