Table 4.

Correlations of PROMIS CAT instruments with patient-reported outcomes at baseline.

PROMIS CAT InstrumentsSF-36 SubscalesSF-36 Summary ScoresGlobal Assessment Scores
VitalPFBPSFMHGHRERPPCSMCSPtGAPGA
Fatigue−0.67*−0.51*−0.52*−0.59*−0.44*−0.44*−0.49*−0.59*−0.65*−0.54*0.48*0.19*
Physical function0.50*0.73*0.53*0.47*0.30*0.40*0.40*0.63*0.81*0.29*−0.43*−0.11*
Pain interference−0.52*−0.51*−0.62*−0.52*−0.40*−0.36*−0.43*−0.54*−0.71*−0.43*0.44*0.07
Applied cognitive abilities0.50*0.36*0.38*0.47*0.46*0.34*0.48*0.44*0.41*0.54*−0.34*−0.12*
Sleep disturbance−0.38*−0.24*−0.28*−0.46*−0.41*−0.26*−0.39*−0.28*−0.31*−0.53*0.32*0.17*
Social participation0.49*0.62*0.50*0.63*0.43*0.34*0.48*0.59*0.72*0.48*−0.51*−0.10
Sleep-related impairment−0.44*−0.21*−0.37*−0.44*−0.40*−0.30*−0.43*−0.37*−0.31*−0.53*0.30*0.13*
Anger−0.24*−0.16*−0.21*−0.34*−0.39*−0.21*−0.34*−0.18*−0.10−0.46*0.21*0.10
Social isolation−0.45*−0.33*−0.32*−0.48*−0.56*−0.31*−0.48*−0.37*−0.30*−0.58*0.23*0.07
Anxiety−0.50*−0.24*−0.34*−0.51*−0.64*−0.33*−0.54*−0.32*−0.21*−0.70*0.20*0.07
PtGA−0.40*−0.40*−0.47*−0.42*−0.25*−0.36*−0.31*−0.45*−0.54*−0.31*1.00*0.29*
PGA−0.16*−0.14*−0.15*−0.18*−0.09*−0.09*−0.14*−0.18*−0.17*−0.15*0.29*1.00*
  • Spearman correlation coefficients between scores from 10 PROMIS CAT domains, SF-36 subscales, SF-36 summary scores, and global assessment scores.

  • * P < 0.05. PROMIS: Patient Reported Outcomes Measurement Information System; CAT: computer adaptive testing; SF-36: Medical Outcomes Study Short Form-36; Vital: Vitality; PF: physical function; BP: bodily pain; SF: social function; MH: mental health; GH: general health; RE: role emotional; RP: role physical; PCS: physical component summary; MCS: mental component summary; PtGA: patient’s global assessment for disease activity; PGA: physician’s global assessment.