Multivariable Cox regression model for ESRD.
| Covariates | Adjusted HR (95% CI) | p |
|---|---|---|
| Time period | 0.14 | |
| 2005–2010 | 1 (reference) | |
| 1999–2004 | 1.35 (0.96–1.88) | |
| 1994–1998 | 0.97 (0.61–1.52) | |
| Age | 0.99 (0.98–1.00) | 0.15 |
| Female | 0.66 (0.47–0.94) | 0.02 |
| Duration of LN | 1.001 (0.997–1.005) | 0.64 |
| Serum creatinine | 1.58 (1.47–1.70) | < 0.001 |
| Activity index | 1.05 (1.01–1.09) | 0.007 |
| Chronicity index | 1.31 (1.23–1.39) | < 0.001 |
| Standard therapy | 0.72 (0.52–0.98) | 0.04 |
ESRD: endstage renal disease; LN: lupus nephritis.