SLICC Feature Not in ACR Classification Criteria | ± Patients with 3 ACR (n = 41) | ±± Patients with 2 ACR (n = 6) | % of Individual SLICC Criteria, n (%) |
---|---|---|---|
Hypocomplementemia | 18 | 5 | 23/79 (29.1) |
Alopecia | 15 | 1 | 16/79 (20.3) |
Total no. with additional hematologic | 13 | 6 | 19/79 (24.1) |
Leukopenia (SLICC only) | 1 | 1 | |
1 additional | 5 | 3 | |
2 additional | 7 | 2 | |
Coombs+ anemia without hemolysis | 6 | 0 | 6/79 (7.6) |
Total no. with additional autoantibodies | 11 | 0 | 11/79 (13.9) |
1 additional | 9 | 0 | |
2 additional | 2 | 0 | |
CNS criteria | 2 | 0 | 2/79 (2.5) |
Acute cutaneous lupus erythematosus | 2 | 0 | 2/79 (2.5) |
Total | 67 | 12 | 79/79 (100) |
↵* All 48 ACR−/SLICC+ have < 4 ACR classification criteria; 47 met ≥ 4 SLICC classification criteria, and 1 met SLICC classification through biopsy-confirmed nephritis and the presence of autoantibodies (excluded from this table).
↵± Patients could have > 1 SLICC classification criteria not present in ACR classification.
↵±± All patients had 2 SLICC classification criteria not present in ACR classification. ACR: American College of Rheumatology; SLICC: Systemic Lupus International Collaborating Clinics; CNS: central nervous system.