Mean autoantibody (RF) concentrations across haplotype groups and by HLA-DRB1 status.
| Haplotype | All, n = 1442 | RF+, n = 1150 | ||||
|---|---|---|---|---|---|---|
| Haplotype+ | Haplotype− | p* | Haplotype+ | Haplotype− | p | |
| VKA | 347 (639) | 321 (676) | < 0.001 | 404 (675) | 415 (746) | 0.27 |
| VRA | 317 (520) | 334 (709) | 0.05 | 374 (548) | 426 (779) | 0.93 |
| LRA | 356 (766) | 321 (623) | 0.95 | 453 (843) | 396 (673) | 0.30 |
| PRA | 231 (579) | 333 (665) | 0.46 | 278 (629) | 415 (723) | 0.13 |
| VRE | 242 (341) | 333 (672) | 0.96 | 292 (357) | 415 (730) | 0.65 |
| DRE | 294 (401) | 331 (672) | 0.05 | 315 (407) | 416 (732) | 0.76 |
| VEA | 298 (635) | 330 (664) | 0.50 | 462 (766) | 411 (721) | 0.79 |
| SKA | 293 (522) | 331 (668) | 0.98 | 345 (554) | 413 (726) | 0.46 |
| PAA | 359 (734) | 322 (645) | 0.66 | 457 (803) | 400 (699) | 0.89 |
| GRQ | 218 (371) | 352 (705) | 0.02 | 273 (400) | 438 (765) | 0.002 |
| SRA | 359 (649) | 325 (666) | 0.47 | 489 (719) | 399 (720) | 0.10 |
| SRE | 415 (968) | 327 (653) | 0.41 | 550 (1089) | 407 (708) | 0.72 |
| LEA | 170 (282) | 332 (667) | 0.09 | 239 (315) | 413 (724) | 0.19 |
| SRL | 315 (518) | 330 (669) | 0.51 | 425 (566) | 410 (726) | 0.72 |
| SKR | 342 (796) | 327 (635) | 0.05 | 463 (900) | 402 (685) | 0.84 |
| SEA | 309 (607) | 334 (673) | 0.09 | 408 (672) | 411 (729) | 0.61 |
| Valine 11 | 329 (597) | 330 (742) | < 0.001 | 390 (633) | 442 (833) | 0.47 |
| SE | 337 (629) | 311 (743) | < 0.001 | 420 (841) | 408 (673) | 0.008 |