Clinical Measures | No. Cases Analyzed | Mean Spearman Coefficient | Minimum Spearman Coefficient | Maximum Spearman Coefficient |
---|---|---|---|---|
Active joint count | 45 | 0.088 | 0.081 | 0.097 |
Swollen joint | 45 | 0.084 | 0.072 | 0.094 |
PGA | 38 | −0.059 | −0.070 | −0.051 |
Parent’s assessment | 15 | −0.166 | −0.180 | −0.143 |
Enthesitis count | 44 | −0.082 | −0.108 | −0.055 |
Hip abduction | 25 | −0.343 | −0.353 | −0.335 |
ESR | 37 | 0.111 | 0.101 | 0.133 |
CRP | 37 | 0.072 | 0.054 | 0.107 |
BASDAI | 29 | −0.013 | −0.022 | −0.002 |
BASFI | 26 | 0.061 | 0.056 | 0.067 |
CHAQ | 18 | −0.039 | −0.039 | −0.039 |
Schober | 44 | 0.575* | 0.563* | 0.583* |
FABER | 44 | 0.255 | 0.251 | 0.258 |
SI joint tenderness | 44 | 0.290 | 0.281 | 0.298 |
Binary clinical measures | No. cases analyzed | Average MRI score (+ vs − test) | Minimum MRI score difference (+ vs − test) | Maximum MRI score difference (+ vs − test) |
FABER | 44 (10+, 34−) | 17.4 vs 6.0 | 16 vs 6.1 | 18.3 vs 6.0 |
SI joint tenderness | 44 (14+, 30−) | 15.0 vs 5.6 | 14.2 vs 5.6 | 15.6 vs 5.6 |
Schober | 44 (6+, 38−) | 28.2 vs 5.5* | 26.3 vs 5.5* | 29.5 vs 5.5* |
Spearman correlation coefficients for continuous or ordinal clinical measures; differences in the mean SPARCC scores are given for binary clinical outcome measures. The mean and range of results are from 4 independent readings (2 readings per 2 radiologists). Only hip abduction and ESR measures remained significantly correlated with SPARCC MRI scores. Statistically significant differences in SPARCC MRI scores were observed between binary clinical outcomes.
↵* P < 0.001 after Bonferroni adjustment. SPARCC: Spondyloarthritis Research Consortium of Canada; MRI: magnetic resonance imaging; PGA: physician’s global assessment; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; CHAQ: Childhood Health Assessment Questionnaire; FABER: Flexion, ABduction, and External Rotation; SI: sacroiliac.