Year	Cases	Controls	p
Index to 1 yr	−14.4 (± 15.3) mg/day	−12.8 (± 20.9) mg/day	0.31
1 yr to 2 yrs after index	−3.0 (± 5.0) mg/day	−4.1 (± 9.8) mg/day	0.31
2 yrs to 3 yrs after index	−1.6 (± 3.3) mg/day	−2.1 (± 7.1) mg/day	0.49
3 yrs to 4 yrs after index	−1.1 (± 2.7) mg/day	−0.5 (± 1.9) mg /day	0.85
4 yrs to 5 yrs after index	0.0 (± 2.2) mg/day	0.7 (± 8.9) mg/day	0.66