Predictor | Univariable | Multivariable | ||
---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |
Female sex | 0.50 | 0.33–0.76 | 0.62 | 0.40–0.97 |
Age, yrs | 0.98 | 0.96–0.99 | ||
BMI (per 1 unit kg/m2) | 0.93 | 0.90–0.96 | ||
BMI > 30 vs ≤ 30 | 0.39 | 0.26–0.60 | 0.51 | 0.32–0.81 |
Baseline CDAI (per 5 units) | 0.76 | 0.67–0.85 | ||
Tender joint count* | 0.92 | 0.88–0.95 | ||
Patient pain (per 10 mm) | 0.76 | 0.70–0.83 | 0.80 | 0.73–0.87 |
Patient global (per 10 units)* | 0.74 | 0.68–0.81 | ||
mHAQ (per 0.125 units) | 0.83 | 0.77–0.89 | ||
College education | 2.31 | 1.41–3.80 | 1.88 | 1.11–3.19 |
Full-time work | 2.67 | 1.71–4.18 | ||
Alcohol intake (yes/no) | 1.75 | 1.14–2.68 | ||
Hypertension | 0.48 | 0.29–0.78 | 0.55 | 0.32–0.95 |
Diabetes | 0.48 | 0.21–1.06 | ||
Cardiovascular disease | 0.49 | 0.17–1.39 | ||
Smoker (previous/current) vs never | 0.78 | 0.52–1.17 | ||
Current methotrexate | 0.88 | 0.59–1.33 | ||
Any previous biologic use | 0.38 | 0.25–0.58 | 0.41 | 0.26–0.65 |
Calendar year | 1.01 | 0.93–1.10 |
Not all variables are shown in this table if they were not significant at the multivariable level. Other univariable relationships can be found in Table 1.
↵* Tender joint counts and patient global are part of the CDAI and thus were not included in the final model. All patients had a baseline CDAI > 2.8 (N = 774). C-statistic = 0.776. BMI: body mass index; CDAI: Clinical Disease Activity Index; mHAQ: modified Health Assessment Questionnaire.