Baseline characteristics of the 344 SLE patients and 344 population-based controls.
| Characteristics | Patients with SLE | Controls |
|---|---|---|
| Background variables | ||
| Age, yrs | 34.0 (12–73) | 34.4 (15–73) |
| Weight, kg | 67.5 (32.6–133.0) | NA |
| Height, cm | 164.6 (145.0–194.5) | NA |
| Female sex | 315 (91.6) | 315 (91.6) |
| Ethnicities | ||
| White | 200 (58.1) | 327 (95.1) |
| African descendants | 52 (15.1) | 4 (1.1) |
| Asian | 64 (18.6) | 3 (0.9) |
| Other | 28 (8.1) | 10 (2.9) |
| Disease variables | ||
| SLEDAI-2K score | 5.0 (0–30) | NA |
| C-reactive protein, mg/l* | 4.6 (0–114) | |
| Erythrocyte sedimentation rate, mm/h# | 23.9 (1–99) | |
| Glucocorticoid dose at baseline, mg/day | 14 (0–90) | |
| Creatinine, mg/dl | 0.7 (0.1–8.1) | |
| eGFR, ml/min/1.73 m2 | 119.9 (6.3–473.2) | |
| Low complement | 130 (37.8) | |
| Increased DNA binding | 150 (43.6) | |
| 1997 ACR criteria (at enrollment) | NA | |
| 1. Malar rash | 111 (32.3) | |
| 2. Discoid rash | 39 (11.3) | |
| 3. Photosensitivity | 131 (38.1) | |
| 4. Oral ulcers | 125 (36.3) | |
| 5. Arthritis | 249 (72.4) | |
| 6. Serositis | 92 (26.7) | |
| 7. Renal disorder | 75 (21.8) | |
| 8. Neurologic disorder | 12 (3.5) | |
| 9. Hematologic disorder | 214 (62.2) | |
| 10. Immunologic disorder | 265 (77.0) | |
| 11. Antinuclear antibody | 336 (97.7) |
Data are presented as mean (range) or n (%).
↵* Performed locally at each SLICC centre (n = 312).
↵# Performed locally at each SLICC centre (n = 167). ACR: American College of Rheumatology; SLE: systemic lupus erythematosus; SLEDAI-2K: SLE Disease Activity Index 2000; eGFR: estimated glomerular filtration rate; SLICC: Systemic Lupus International Collaborating Clinics; NA: not applicable.