Table 3.

Proportion of patients in discordance for each pair of LDA definitions at Week 24.

LDA Definition 1LDA Definition 2Proportion of Patients Achieving LDA 2 but Not LDA 1, n/N (%)Proportion of Patients Achieving LDA 1 but Not LDA 2, n/N (%)κ Coefficient*
MDA 5/7DAPSA LDA184/669 (27.5)10/669 (1.5)0.45
MDA skinDAPSA LDA346/668 (51.8)7/668 (1.0)0.15
MDA jointDAPSA LDA225/668 (33.7)1/665 (0.1)0.39
MDA joint + skinDAPSA LDA373/669 (55.8)1/669 (0.1)0.13
MDA 5/7cDAPSA LDA183/676 (27.1)10/676 (1.5)0.45
MDA skincDAPSA LDA347/675 (51.4)7/675 (1.0)0.16
MDA jointcDAPSA LDA225/675 (33.3)1/675 (0.1)0.40
MDA joint + skincDAPSA LDA375/676 (55.5)1/676 (0.1)0.13
  • * From κ test of agreement between LDA definition 1 and definition 2. LDA: low disease activity; MDA: minimal disease activity; DAPSA: Disease Activity for Psoriatic Arthritis; cDAPSA: clinical DAPSA.