A comparison of variables at the time of SSc between a cohort that subsequently developed SRC and a cohort that did not develop SRC. Data are %, n/N unless otherwise specified.
| Variables | SRC, n = 31 | SSc without SRC, n = 322 | p |
|---|---|---|---|
| Serum creatinine, mg/dl, median (IQR) | 0.98 (0.9–1.1) | 0.8 (0.7–0.9) | < 0.001 |
| eGFR, cc/min/1.73 m2, median (IQR) | 76 (56–86) | 96 (80–110) | < 0.001 |
| CKD, < 60 cc/min/1.73 m2 | 33, 9/27 | 3, 8/312 | < 0.001 |
| Hypertension, > 140/90 mmHg or meds | 81, 25/31 | 24, 72/305 | < 0.001 |
| Proteinuria, ≥ +1 on UA | 50, 14/28 | 1, 3/312 | < 0.001 |
| Average Hgb, g/dl, median (IQR) | 11.8 (10.3–13.1) | 13.4 (12.7–14.1) | < 0.001 |
| Anemia | 55, 17/31 | 6, 18/309 | < 0.001 |
| Average ESR, g/dl | 35, 20/47 | 16, 8/20 | < 0.001 |
| ESR, % elevated | 68, 17/25 | 15, 38/261 | < 0.001 |
| Average platelets, K/µl | 244, 152/335 | 265, 216/304 | 0.03 |
| Platelet, % low | 23, 7/31 | 3, 8/309 | < 0.001 |
SRC: scleroderma renal crisis; SSc: systemic sclerosis; IQR: interquartile range; eGFR: estimated glomerular filtration rate; CKD: chronic kidney disease; UA: urinalysis; ESR: erythrocyte sedimentation rate; Hgb: hemoglobin.