Multivariable logistic regression model of clinical factors associated with scleroderma renal crisis.
| Logistic Regression Models | OR | 95% CI | p |
|---|---|---|---|
| CKD* | 20.7 | 2.2–190.7 | 0.008 |
| Hypertension** | 13.1 | 4.7–36.6 | < 0.001 |
| Proteinuria† | 183 | 19.1–1750 | < 0.001 |
| Anemia‡ | 9.9 | 2.7–36.2 | 0.001 |
| ESR£ | 14.3 | 4.8–43.0 | < 0.001 |
| Thrombocytopenia‖ | 7.0 | 1.2–42.7 | 0.003 |
| Hypothyroidism¥ | 2.8 | 1.2–6.7 | 0.01 |
| ARAπ | 4.1 | 1.2–13.8 | 0.02 |
| Ro antibodyπ | 3.9 | 1.6–9.8 | 0.03 |
↵* Adjusted for hypertension, proteinuria, age, race, and ESR.
↵** Adjusted for age, race, sex, CKD, and hypothyroidism.
↵† Adjusted for hypertension, ESR, and CKD.
↵‡ Adjusted for ESR, CKD, cancer, hypothyroidism, and low platelets.
↵£ Adjusted for age, cancer, and CKD.
↵‖ Adjusted for hypertension, ESR, cancer, and anemia.
↵¥ Adjusted for age and sex.
↵π Adjusted for ANA seropositivity. CKD: chronic kidney disease; ESR: erythrocyte sedimentation rate; ARA: anti-RNA polymerase III antibodies; ANA: antinuclear antibodies.