Minimal clinically important improvement (MCII) estimates for RAPID-3, using either the minimal distance to 0.1 on the receiver-operating characteristic curve (which maximizes specificity and sensitivity simultaneously), a set specificity of 0.80, or the Youden index as the criterion, and the subjective change in global arthritis status as the standard. Values are based on the mean of 2000 bootstrapped samples.
| Criterion | MCII (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | % Misclassified |
|---|---|---|---|---|
| Minimal distance to 0.1 | −3.8 (−3.1 to −4.4) | 0.71 (0.66–0.77) | 0.84 (0.79–0.90) | 24.9 |
| Specificity 0.80 | −3.5 (−2.9 to −4.3) | 0.71 (0.65–0.78) | 0.80 (0.78–0.82) | 25.3 |
| Youden index | −4.1 (−3.6 to −4.6) | 0.69 (0.63–0.76) | 0.87 (0.81–0.94) | 24.9 |
RAPID-3: Routine Assessment of Patient Index Data 3.