Univariate and multivariate analyses for assessing predictors of abnormal BNP/cTnI.
| Predictor | OR | Lower 95% Confidence Limit | Upper 95% Confidence Limit | Pr > Chi-square |
|---|---|---|---|---|
| Univariate analysis | ||||
| Age at test | 1.047 | 1.002 | 1.094 | 0.0413 |
| SLE duration at test | 1.064 | 1.014 | 1.116 | 0.0114 |
| eGFR at test | 0.973 | 0.954 | 0.991 | 0.0039 |
| Hypertension at test | 3.025 | 1.042 | 8.776 | 0.0417 |
| Diuretics treatment at test | 8.183 | 2.288 | 29.268 | 0.0012 |
| CPK abnormal | 3.951 | 1.346 | 11.598 | 0.0124 |
| Cumulative AM dose | 1.105 | 1.031 | 1.184 | 0.0045 |
| Yrs taking AM, cumulative (> 5.6 yrs) | 1.069 | 1.015 | 1.125 | 0.0119 |
| Multivariate analysis | ||||
| eGFR | 0.978 | 0.957 | 0.999 | 0.0362 |
| Diuretics | 4.218 | 1.078 | 16.503 | 0.0386 |
| CPK abnormal | 4.624 | 1.221 | 17.511 | 0.0242 |
| Yrs taking AM, cumulative (> 5.6 yrs) | 5.431 | 1.14 | 25.881 | 0.0337 |
eGFR: estimated glomerular filtration rate; CPK: creatine phosphokinase; AM: antimalarials; BNP: brain natriuretic peptide; cTnI: cardiac troponin I; SLE: systemic lupus erythematosus.