Other clinical features of HOSTAS cohort.
| Variables | anti-CarP+, n = 36 | anti-CarP−, n = 471 | p | RF+, n = 30 | RF−, n = 477 | p |
|---|---|---|---|---|---|---|
| Sum-score KL (0–120)a | 17.5 (9.5–30.75) | 18.0 (8.0–29.0) | 0.74 | 13.5 (8.75–30.5) | 18.0 (8.0–30.5) | 0.59 |
| Sum-score OARSI osteophytes (0–58)a | 9.5 (6.0–19.0) | 10.0 (4.0–18.0) | 0.64 | 8.0 (4.75–16.25) | 10.0 (4.5–18.0) | 0.74 |
| Sum-score OARSI joint space narrowing (0–58)a | 5.5 (3.0–16.75) | 7.0 (3.0–17.0) | 0.72 | 6.5 (2.75–18.0) | 7.0 (3.0–17.0) | 0.98 |
| CRP raised (> 5.0 mg/l)b, % (n/total) | 11.5 (3/26) | 10.4 (34/326) | 0.86 | 7.7 (2/26) | 10.7 (35/326) | 0.63 |
Values are median (IQR) unless otherwise specified.
↵a For 3 patients, no hand radiographs were available; Mann-Whitney U test was performed.
↵b Only 352 patients had their CRP levels measured within 22 days from baseline; Pearson’s chi-square test was performed. Anti-CarP: anticarbamylated protein antibodies; RF: rheumatoid factor; KL: Kellgren-Lawrence arthritis grading scale; OARSI: Osteoarthritis Research Society International; CRP: C-reactive protein; IQR: interquartile range.