Table 4.

Correlation of EPC populations with growth factors and cytokines expressed in bone tissue.

RANKLPDGFBVEGFAAng-1Ang-2OSXOPGRUNX2VEGFCCD31EMCNHIFCTSK
C0.008−0.1540.532*0.2870.2570.2390.0550.1940.3040.2180.020−0.0540.146
C1−0.594*−0.314−0.3530.550*−0.262*0.1330.0090.432*−0.2010.449*0.250−0.2280.101
C20.676**0.1540.2070.2430.484*0.1360.161−0.0520.134−0.343−0.150−0.006−0.168
C30.0050.2300.549*−0.450−0.167−0.329−0.240−0.225−0.074−0.059−0.047−0.034−0.338
C40.720**0.082−0.3030.2060.2800.0140.207−0.523*0.1740.427−0.1860.106−0.108
  • * Correlation is significant at the 0.05 level (2-tailed).

  • ** Correlation is significant at the 0.01 level (2-tailed). C = CD34+ cells; C1 = CD34+CD133–KDR+ cells; C2 = CD34+CD133+KDR+ cells; C3 = CD34+/CD133−/KDR− cells; C4 = CD34+/CD133+/KDR− cells; RANKL: receptor activator of nuclear factor-κB ligand; PDGFB: platelet-derived growth factor B; VEGFA: vascular endothelial growth factor A; Ang-1: angiopoietin 1; Ang-2: angiopoietin 2; OSX: osterix; OPG: osteoprotegerin; RUNX2: runt-related transcription factor 2; VEGFC: vascular endothelial growth factor C; EMCN: endomucin; HIF: hypoxia-inducible factor; CTSK: cathepsin K.