Distribution of lesion feature scores by visit and activity status.
| Visit 1 | Visit 2 | Visit 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Lesion Feature and Score | Inactive | Active | p | Inactive | Active | p | Inactive | Active | p |
| Erythema | < 0.001 | 0.001 | 0.016 | ||||||
| None | 23 (95.8) | 23 (34.9) | 22 (95.7) | 30 (52.6) | 20 (95.2) | 36 (62.1) | |||
| Mild | 1 (4.2) | 30 (45.5) | 1 (4.4) | 25 (43.9) | 1 (4.8) | 20 (34.5) | |||
| Moderate | 0 (0.0) | 13 (19.7) | 0 (0.0) | 2 (3.5) | 0 (0.0) | 2 (3.5) | |||
| Severe | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
| Violaceous color | 0.013 | 0.017 | 0.042 | ||||||
| None | 24 (100) | 47 (71.2) | 23 (100) | 45 (79.) | 21 (100.) | 48 (82.8) | |||
| Mild | 0 (0.0) | 16 (24.2) | 0 (0.0) | 12 (21.1) | 0 (0.0) | 10 (17.3) | |||
| Moderate | 0 (0.0) | 3 (4.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
| Severe | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
| STE | NS | NS | NS | ||||||
| None | 15 (62.5) | 34 (51.5) | 15 (65.2) | 31 (54.4) | 16 (76.2) | 44 (75.9) | |||
| Mild | 9 (37.5) | 22 (33.3) | 6 (26.1) | 22 (38.6) | 5 (23.8) | 11 (19.0) | |||
| Moderate | 0 (0.0) | 8 (12.1) | 2 (8.7) | 4 (7.0) | 0 (0.0) | 3 (5.2) | |||
| Severe | 0 (0.0) | 2 (3.03) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
| STC | NS | NS | NS | ||||||
| None | 10 (41.7) | 22 (33.3) | 11 (47.8) | 22 (38.6) | 11 (52.4) | 24 (41.4) | |||
| Mild | 7 (29.2) | 17 (25.8) | 8 (34.8) | 19 (33.3) | 7 (33.3) | 19 (32.8) | |||
| Moderate | 7 (29.2) | 24 (36.4) | 4 (17.39) | 15 (26.3) | 3 (14.3) | 15 (25.9) | |||
| Severe | 0 (0.0) | 3 (4.6) | 0 (0.0) | 1 (1.8) | 0 (0.0) | 0 (0.0) | |||
| SQ atrophy | NS | NS | NS | ||||||
| None | 9 (37.5) | 23 (34.9) | 5 (21.7) | 11 (19.3) | 9 (42.9) | 16 (27.6) | |||
| Mild | 9 (37.5) | 29 (43.9) | 15 (65.2) | 33 (57.9) | 8 (38.1) | 29 (50.0) | |||
| Moderate | 5 (20.8) | 11 (16.7) | 2 (8.7) | 8 (14.0) | 4 (19.1) | 11 (19.0) | |||
| Severe | 1 (4.2) | 3 (4.6) | 1 (4.4) | 5 (8.8) | 0 (0.0) | 2 (3.5) | |||
| Dyspigmentation | NS | NS | NS | ||||||
| None | 3 (12.5) | 7 (10.6) | 3 (13.) | 5 (8.8) | 3 (14.3) | 7 (12.3) | |||
| Mild | 8 (33.3) | 31 (45.0) | 12 (52.2) | 29 (50.9) | 11 (52.4) | 26 (45.6) | |||
| Moderate | 12 (50.0) | 21 (31.8) | 6 (26.1) | 21 (36.8) | 6 (28.6) | 21 (36.8) | |||
| Severe | 1 (4.2) | 7 (10.6) | 2 (8.7) | 2 (3.5) | 1 (4.76) | 3 (5.3) | |||
The distribution of scores for lesion features scored on a 0 to 3 range were examined in active and inactive lesions. The left column lists the lesion features and their scoring levels. The n (%) of lesions with each of the scoring level scores are shown for active and inactive lesion groups at each visit. P values were calculated for the distribution of the scores in active compared to inactive group at each visit. NS: not significant; STE: skin thickening of the lesion edge; STC: skin thickening of the lesion center; SQ atrophy: subcutaneous atrophy.