Table 2.

Clinical characteristics of JIA patients with or without underlying IBD. Values are n (%) or mean (SD, range).

CharacteristicsIBD, n = 7Non-IBD, n = 106
Age, yrs11.2 (2.5, 8.3–16.4)9.0 (5.0, 1.7–19.3)
No. females5 (71)83 (78)
Oligoarticular JIA2 (29)74 (70)
Polyarticular JIA0 (0)27 (25)
Enthesitis-related arthritis4 (57)2 (2)
Psoriatic arthritis0 (0)3 (3)
Undifferentiated arthritis1 (14)0 (0)
Presence of ANA1 (14)51 (48)
Duration of JIA, mos19.4 (23.7, 0–52)40.11 (37.44, 2–125)
Presence of GI symptoms3 (43)3 (3)*
Presence of growth failure3 (43)0 (0)*
ESR, mm/h66.71 (23.91, 53–88)25.88 (13.9, 2–120)*
CRP, mg/dl3.03 (1.42, 1.2–5.76)0.42 (0.79, 0–4.51)*
White blood count, n/mm39332 (3853; 5570–17,010)7738 (2201; 4260–19,160)
Platelet count, n/mm3415,285 (74,365; 283,000–477,000)314,351 (86,020; 163,000–604,000)
Hemoglobin, g/dl11.3 (1.3, 9.5–13)12.4 (1.1, 9.4–15.3)
IgG levels, mg/dl1419 (431, 1002–1983)1147 (386, 546–2235)
IgA levels, mg/dl326 (130, 189–500)134 (85, 5–415)*
  • * p < 0.0001.

  • p < 0.05. IBD: inflammatory bowel disease; JIA: juvenile idiopathic arthritis; ANA: antinuclear antibodies; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; GI: gastrointestinal.