Table 5.

Pregnancy and SLE (n = 130 responders*).

Questionnaire ItemsMode (% responders)Commonly Repeated Strategies (% responders)
Preconception counseling ensuring disease quiescence for at least 6 mos, n = 130Yes (85)Sometimes (6), other (6), no (3), never (0)
Length of time to have discontinued a bisphosphonate, n = 128Do not use bisphosphonates in childbearing women (48)6–12 mos (16), 3–6 mos (15), 12–18 mos (9), 18–24 mos (2), > 24 mos (2)
Discontinuation or lack of initiation of the following nonteratogenic medications when attempting conception or are pregnant:
  HCQ, n = 128No (77)Yes (9), sometimes (9)
  Chloroquine, n = 124No (52)Sometimes (19), yes (13)
  AZA, n = 128No (52)Yes (21), sometimes (19)
Discontinuation or lack of initiation of the following nonteratogenic medications when breastfeeding:
  HCQ, n = 126No (79)Sometimes (7), yes (6)
  Chloroquine, n = 123No (53)Yes (15), sometimes (9)
  AZA, n = 126No (37)Yes (29), sometimes (21)
Does estrogen-containing oral contraceptives increase the risk of flare in SLE?
  Yes28 (22)
  No60 (46)
  I do not know41 (32)
Do you advise SLE patients without APS to use the following forms of contraception?
  Low-dose estrogen, n = 126Always (22)Sometimes (62), never (16)
  Moderate-dose estrogen, n = 125Always (2)Sometimes (3), never (66)
  High-dose estrogen, n = 124Always (0)Sometimes (7), never (93)
  Progesterone only, n = 126Always (12)Sometimes (58), never (30)
  IUD, n = 124Always (18)Sometimes (68), never (15)
  Hormone-releasing IUD, n = 124Always (14)Sometimes (46), never (40)
  Abstinence, n = 125Always (3)Sometimes (11), never (86)
  Rhythm method, n = 124Always (2)Sometimes (6), never (93)
Do you advise SLE patients with APS to use the following forms of contraception?
  Low-dose estrogen, n = 126Always (5)Sometimes (27), never (68)
  Moderate-dose estrogen, n = 124Always (0)Sometimes (6), never (96)
  High-dose estrogen, n = 125Always (0)Sometimes (2), never (98)
  Progesterone only, n = 127Always (13)Sometimes (42), never (45)
  IUD, n = 126Always (30)Sometimes (53), never (17)
  Hormone-releasing IUD, n = 122Always (17)Sometimes (39), never (43)
  Abstinence, n = 124Always (3)Sometimes (13), never (84)
  Rhythm method, n = 125Always (2)Sometimes (7), never (91)
  • * The n is provided per question because responders were given the option to skip questions that were not applicable to their practice. SLE: systemic lupus erythematosus; HCQ: hydroxychloroquine; AZA: azathioprine; APS: antiphospholipid antibody syndrome; IUD: intrauterine device.