Demographics of the patients with rheumatoid arthritis (n = 745) after stratification for antibody status (ACPA and anti-PAD4).
| ACPA+ | ACPA− | |||||
|---|---|---|---|---|---|---|
| anti-PAD4+ | anti-PAD4− | p | anti-PAD4+ | anti-PAD4− | p | |
| Total | 149 | 317 | 44 | 235 | ||
| Sex (% women) | 121 (81.2) | 244 (77.0) | 0.30 | 39 (88.6) | 175 (74.5) | 0.04 |
| RF (% positive) | 106 (74.1) | 223 (74.6) | 0.92 | 13 (30.2) | 39 (17.3) | 0.05 |
| SE (% positive) | 128 (87.1) | 268 (86.2) | 0.79 | 20 (46.5) | 127 (55.7) | 0.27 |
| Smoke (% ever smokers) | 73 (54.5) | 196 (69.0) | 0.004 | 21 (53.8) | 139 (63.5) | 0.25 |
| Age at onset, yrs, mean (SD) | 45.9 (14.4) | 47.9 (14.9) | 0.18 | 49.1 (17.2) | 47.6 (16.9) | 0.58 |
ACPA: anticitrullinated protein antibodies; anti-PAD4: antipeptidyl arginine deiminase type 4; RF: rheumatoid factor; SE: shared epitope.