Table 2.

Comparative performance of CV risk scores against 3 quantitative measurements of coronary artery plaque.

Risk Scores	Total Plaque Volume			Segment Involvement Score			Segment Stenosis Scale
Risk Scores	High Risk	Low Risk	p	High Risk	Low Risk	p	High Risk	Low Risk	p
FRS	1.7 ± 2.6, n = 19	1.07 ± 1.5, n = 31	0.22	2.7 ± 2.2, n = 19	1.6 ± 1.8, n = 31	0.050	5.1 ± 6.4, n = 19	3.2 ± 3.4, n = 31	0.39
m-FRS	1.8 ± 2.4, n = 24	0.8 ± 1.5, n = 26	0.009	2.9 ± 2.0, n = 24	1.2 ± 1.6, n = 26	0.001	5.5 ± 5.8, n = 24	2.3 ± 3.0, n = 26	0.03
SCORE	2.2 ± 2.9, n = 14	0.9 ± 1.4, n = 36	0.08	2.9 ± 2.2, n = 13	1.7 ± 1.8, n = 37	0.07	6.0 ± 7.1, n = 13	3.1 ± 3.5, n = 37	0.22
m-SCORE	2.1 ± 2.6, n = 22	0.7 ± 1.07, n = 28	0.003	3.1 ± 2.1, n = 22	1.2 ± 1.4, n = 28	< 0.001	5.8 ± 5.9, n = 22	2.3 ± 3.1, n = 28	0.01
QRISK2	1.4 ± 1.4, n = 12	1.3 ± 2.2, n = 38	0.30	3.0 ± 2.3, n = 12	1.7 ± 1.8, n = 38	0.06	6.6 ± 7.2, n = 12	3.0 ± 3.5, n = 38	0.09
m-QRISK2	1.5 ± 1.4, n = 22	1.2 ± 2.4, n = 28	0.04	2.7 ± 2.1, n = 22	1.5 ± 1.7, n = 28	0.01	5.3 ± 5.9, n = 22	2.8 ± 3.5, n = 28	0.06
ASCVD	1.7 ± 2.5, n = 27	0.8 ± 1.0, n = 23	0.20	2.3 ± 2.0, n = 27	1.6 ± 1.9, n = 23	0.12	4.7 ± 5.7, n = 27	2.9 ± 3.5, n = 23	0.28
m-ASCVD	1.6 ± 2.2, n = 36	0.4 ± 0.7, n = 14	0.001	2.5 ± 2.1, n = 36	0.85 ± 1.0, n = 14	0.007	4.7 ± 5.3, n = 36	1.7 ± 2.0, n = 14	0.04

Results are presented as mean ± SD. The standard cutoff values were used to define high risk of CV disease for the general population: FRS > 10%, QRISK2 > 20%, SCORE > 5%, and ASCVD > 7.5%. The EULAR recommended modifications (multiplication factor by 1.5) were also applied for 4 CV risk scores and labeled as m-FRS, m-SCORE, m-QRISK2, and m-ASCVD. CV: cardiovascular; FRS: Framingham risk score; SCORE: Systematic Coronary Risk Evaluation; ASCVD: Atherosclerotic Cardiovascular Disease score; EULAR: European League Against Rheumatism.