Potential predictors of in-hospital gout flares. Values are n (%) or mean ± SD unless otherwise specified.
| Predictors | Value* | OR (95% CI) |
|---|---|---|
| Diagnosis year 2009–2010 (vs 1989–1992) | 306 (56) | 1.47 (0.65–3.35) |
| Age at gout diagnosis, yrs, per 10-yr increase | 59.7 ± 17.3 | 1.15 (0.86–1.55) |
| Male sex | 312 (73) | 1.08 (0.46–2.56) |
| Time since most recent flare prior to hospitalization, per 1-year increase | 3.4 ± 4.0 | 0.87 (0.74–1.02) |
| No. flares prior to hospitalization | 2.7 ± 2.2 | 1.04 (0.88–1.23) |
| > 1 joint affected at gout diagnosis | 861 (12) | 1.75 (0.60–5.06) |
| Joint other than 1st MTP affected at gout diagnosis | 253 (36) | 1.31 (0.57–3.03) |
| Had ULT at hospital admission | 211 (30) | 0.36 (0.11–1.01) |
| Started ULT within 3 months prior to hospitalization | 27 (8) | 2.82 (0.71–11.25) |
| ULT discontinued at/during hospitalization | 18 (4) | 0.86 (0.11–6.83) |
| ICU stay during hospitalization | 61 (13) | 1.24 (0.45–3.42) |
| Taking diuretics during hospitalization | 248 (55) | 1.46 (0.64–3.30) |
| Kidney disease | 325 (46) | 0.91 (0.40–2.06) |
| Serum uric acid level at gout diagnosis, mg/dl | 8.7 ± 1.9 | 1.40 (1.11–1.77) |
| BMI at hospital admission, kg/m2 | 29.2 ± 7.8 | 0.99 (0.94–1.05) |
| Obesity at hospital admission, BMI ≥ 30 kg/m2 | 244 (37) | 0.80 (0.33–1.96) |
| Obesity at hospital admission, BMI ≥ 35 kg/m2 | 120 (18) | 1.43 (0.52–3.90) |
| Morbid obesity at hospital admission, BMI ≥ 40 kg/m2 | 63 (10) | 1.97 (0.61–6.39) |
↵* Values based on no. hospitalizations, not no. unique patients. ULT: urate-lowering therapy; MTP: metatarsophalangeal joint; ICU: intensive care unit; BMI: body mass index.