Lectin pathway protein concentrations in serum of 372 patients with SLE and 170 healthy controls. Values are μg/ml (range) unless otherwise specified.
| Lectin Pathway Proteins | Patients with SLE, n = 372, Median Serum Concentration | Controls, n = 170, Median Serum Concentration | p |
|---|---|---|---|
| MBL | 1.634 (0–9.976) | 1.342 (0–10.080) | 0.600 |
| M-ficolin | 2.387 (0.528–7.297) | 2.563 (1.063–7.627) | 0.003 |
| L-ficolin* | 3.125 (0.281–9.355) | 2.432 (0.982–4.307) | < 0.001 |
| H-ficolin | 44.05 (0.332–166.7) | 35.380 (7.469–96.11) | 0.001 |
| CL-L1 | 0.466 (0.254–0.745) | 0.491 (0.348–0.743) | < 0.001 |
| CL-K1 | 0.469 (0.276–0.815) | 0.505 (0.203–0.727) | < 0.001 |
| MASP-1 | 10.73 (2.944–38.75) | 11.350 (3.512–21.66) | 0.594 |
| MASP-3 | 7.287 (2.750–22.29) | 6.344 (1.702–14.16) | < 0.001 |
| MAp44 | 2.436 (1.053–8.674) | 2.251 (1.185–4.532) | < 0.001 |
| MASP-2 | 0.545 (0.065–3.612) | 0.391 (0.051–1.592) | < 0.001 |
| MAp19 | 0.366 (0.100–0.990) | 0.404 (0.139–0.859) | 0.001 |
↵* L-ficolin concentrations were measured only in patients for whom EDTA plasma was available (n = 169). SLE: systemic lupus erythematosus; MBL: mannan binding lectin.