Demographic and clinical characteristics of patients dichotomized based on CCL-18 status. Values are mean ± SD or n (%) unless otherwise specified.
| Characteristics | CCL-18–positive, n = 24 | CCL-18–negative, n = 58 | p |
|---|---|---|---|
| Age at disease onset, yrs | 55.5 ± 10.3 | 52.8 ± 11.3 | 0.25 |
| Disease duration, yrs | 2.3 ± 1.7 | 2.4 ± 1.4 | 0.55 |
| Male sex | 6 (25) | 12 (21) | 0.67 |
| African American | 6 (25) | 12 (21) | 0.67 |
| Disease type, diffuse | 13 (54) | 32 (55) | 0.93 |
| Immunosuppression | 7 (29) | 30 (52) | 0.06 |
| FVC% at baseline | 73.4 ± 15.2 | 76 ± 18.3 | 0.56 |
| mRSS | 17.7 ± 12.2 | 16.3 ± 11.1 | 0.67 |
| Anti-Scl 70 | 7 (30) | 10 (17) | 0.19 |
| Anti-RNA polymerase III | 4 (17) | 16 (28) | 0.40 |
| Anticentromere | 1 (4) | 4 (7) | 1.00 |
FVC%: % forced vital capacity; mRSS: modified Rodnan skin score.