Characteristics | axSpA/IBD, n = 45 | per-SpA/IBD, n = 40 | IBD, n = 40 | p |
---|---|---|---|---|
Sex, male | 25 (54.8) | 9 (21.7) | 22 (55) | 0.023# |
Age, yrs, median (IQR) | 43 (37.5–45) | 51 (37–61.5) | 44.5 (36.3–59.5) | 0.474 |
Smoker° | 15 (33) | 8 (20) | 10 (25) | 0.094# |
IBD, CD:UC | 28 (61):17 (39) | 23 (57.5):17 (42.5) | 25 (62.5):15 (37.5) | 0.928 |
Active IBD, CD:UC§ | 30 (68):15 (33) | 18 (46):22 (64) | 24 (60):16 (40) | 0.476 (CD), 0.268 (UC) |
Duration of IBD, yrs, median (IQR) | 12 (5–14.5) | 5 (0.5–16) | 1 (0.8–6.3)*∞ | < 0.001* |
Undergoing corticosteroid therapy | 10 (22.6) | 10 (26.1) | 18 (45) | 0.109# |
Duration of articular symptoms, mos, median (IQR) | 24 (12–60)*◊ | 10 (3–16) | NA | < 0.001* |
Nonradiographic axSpA+,3,14 | 38 (84) | NA | NA | NA |
AS+,3,14 | 7 (16) | NA | NA | NA |
CDAI17 | 358.89 ± 150 | 301.09 ± 180 | 334.14 ± 80 | 0.110 |
pMAYO18 | 5.8 ± 1.50 | 6 ± 0.92 | 4.8 ± 2.53 | 0.089 |
ASDAS-CRP19 | 2.87 ± 1.00 | 2.66 ± 0.63 | NA | 0.984 |
BASDAI20 | 5.32 ± 2.16 | 4.47 ± 1.81 | NA | 0.152 |
BASFI21 | 2.54 ± 2.44 | 2.30 ± 1.98 | NA | 0.872 |
CRP | 2.05 ± 2.65 | 2.09 ± 3.80 | 1.98 ± 1.80 | 0.818 |
All data were recorded at the time of evaluation.
↵° Considered also as previous habit.
↵§ IBD activity evaluated with CDAI for CD and pMayo score for UC.
↵Statistical analysis performed with *Kruskal-Wallis test (in the case of p < 0.05, the result of the multiple comparisons is shown in bold face) or
↵# Fisher’s exact test.
↵∞ p value axSpA/IBD vs p value IBD = 0.015.
↵◊ p value axSpA/IBD vs p value per-SpA/IBD = 0.001.
↵+ According to ASAS and modified New York criteria. ASAS: Ankylosing Spondylitis Assessment Society; IBD: inflammatory bowel disease; SpA/IBD: IBD-associated spondyloarthritis with articular axial (ax-) or peripheral (per-) involvement (radiographic or magnetic resonance imaging); IQR: interquartile range; CD: Crohn disease; UC: ulcerative colitis; axSpA: axial spondyloarthritis; AS: ankylosing spondylitis; CDAI: Crohn Disease Activity Index; pMAYO: partial Mayo score; ASDAS-CRP: Ankylosing Spondylitis Disease Activity Score–C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; NA: not applicable.