Table 1.

Demographic and clinical patient characteristics (n = 138,240). Values are n (%) unless otherwise specified.

CharacteristicsValues
Age, mean ± SD, yrs54.2 ± 13.3
Female108,341 (78.4)
Payer type
  National Health Insurance129,054 (93.4)
  Medicaid9186 (6.6)
Institution
  Tertiary hospital20,300 (14.7)
  General hospital14,052 (10.2)
  Community hospital7729 (5.6)
  Clinic77,797 (56.3)
  Other18,362 (13.3)
Physician specialty
  Rheumatology58,776 (42.5)
  Orthopedic surgery27,542 (19.9)
  Other51,922 (37. 6)
Comorbidities
  Hyperparathyroidism429 (0.3)
  Hyperthyroidism10,804 (7.8)
  ESRD3000 (2.2)
  Chronic pulmonary disease45,299 (32.8)
  IBD2480 (1.8)
Medication
  RA-related*
    MTX67,124 (48.6)
    Biologic agent3561 (2.6)
    NSAID133,380 (96.5)
    PPI61,150 (44.3)
  Osteoporosis-related*
    Antiosteoporotic agent66,366 (48.0)
    Anticoagulant2199 (1.6)
    Thyroid hormone8685 (6.3)
    Antidepressant9409 (6.8)
  Oral GC use, mean ± SD
    Duration, mos24.5 ± 24.0
    Mean dose, mg/day6.1 ± 4.7
    Highest dose, mg/day16.2 ± 15.8
  • * Use of medication longer than 3 months during followup period. RA: rheumatoid arthritis; ESRD: endstage renal disease; IBD: inflammatory bowel disease; MTX: methotrexate; NSAID: nonsteroidal antiinflammatory drugs; PPI: proton pump inhibitor; GC: glucocorticoids.