Table 2.

Comparisons of renal pathological data. Values are % or median (IQR) or both unless otherwise specified.

Variables	Groups
Variables	NC	SC	C1	C2
No. patients	59	59	64	49
ISN/RPS class
Class III	20.3	15.3	12.5	6.2^a
Class IV	47.5	50.8	56.3	67.3^a
Class V + III/V + IV	32.2	33.9	31.2	26.5
Crescents, median (IQR), %	0	6.06 (3.57–12.5)	11.44 (7.55–15.19)^b	37.04 (30.04–62.31)^{^b,^c}
Segmental crescents	0	6.06 (3.57–12.5)	5.13 (2.45–9.30)^b	21.74; (13.2–27.53)^{^b,^c}
Circumferential crescents	0	0	5.26 (3.23–7.48)	15.63 (6.93–39.17)^c
Sclerotic glomeruli, median (IQR), %	1.96 (0–10.53)	0 (0–7.43)	1.85 (0–8.99)	4.65 (0–10)
Mesangial proliferation	1 (1–1)	1 (1–1)	1 (1–2)	1 (1–2)^{^a,^b}
Endothelial cells proliferation	78.0	84.5	84.1	81.6
Karyorrhexis/fibrinoid necrosis	1.7	10.2	12.5^a	14.3^a
Subendothelial deposit	56.3	72.9	67.9	64.3
Tubulitis	18.6	33.9	39.1^a	44.9^a
Interstitial infiltration	1 (1–1)	1 (1–1)	1 (1–1)	1 (1–2)^{^a,^b,^c}
Interstitial fibrosis	0 (0–1)	0 (0–1)	0 (0–1)	0 (0–1)
Arteriole thrombosis	3.4	3.4	1.6	2.0
Immunofluorescence of glomerulus
IgM	2 (1–2)	2 (1–3)	2 (1–2)	2 (1–2)
IgG	1 (0–2)	1 (0–2)	1 (0–2)	1 (0–1)
IgA	2 (1–3)	2 (1–3)	2 (1–3)	2 (0.5–2.5)^b
C3	3 (2–3)	3 (3–4)	3 (3–3)	3 (3–3)
C4	1 (0–2)	1 (0–2)	1 (0–2)	1 (0–2)
C1q	2 (1–3)	3 (2–3)^a	2 (1.75–3)^b	2 (1–3)^b

↵a p < 0.05 compared with NC group.
↵b p < 0.05 compared with SC group.
↵c p < 0.05 compared with C1 group. IQR: interquartile range; ISN/RPS: International Society of Nephrology/Renal Pathology Society; IgM: immunoglobulin M; C3: complement factor 3; NC: noncrescent group; SC: segmental crescent group.