Table 2.

Comparisons of renal pathological data. Values are % or median (IQR) or both unless otherwise specified.

VariablesGroups
NCSCC1C2
No. patients59596449
ISN/RPS class
  Class III20.315.312.56.2a
  Class IV47.550.856.367.3a
  Class V + III/V + IV32.233.931.226.5
Crescents, median (IQR), %06.06 (3.57–12.5)11.44 (7.55–15.19)b37.04 (30.04–62.31)b,c
  Segmental crescents06.06 (3.57–12.5)5.13 (2.45–9.30)b21.74; (13.2–27.53)b,c
  Circumferential crescents005.26 (3.23–7.48)15.63 (6.93–39.17)c
Sclerotic glomeruli, median (IQR), %1.96 (0–10.53)0 (0–7.43)1.85 (0–8.99)4.65 (0–10)
Mesangial proliferation1 (1–1)1 (1–1)1 (1–2)1 (1–2)a,b
Endothelial cells proliferation78.084.584.181.6
Karyorrhexis/fibrinoid necrosis1.710.212.5a14.3a
Subendothelial deposit56.372.967.964.3
Tubulitis18.633.939.1a44.9a
Interstitial infiltration1 (1–1)1 (1–1)1 (1–1)1 (1–2)a,b,c
Interstitial fibrosis0 (0–1)0 (0–1)0 (0–1)0 (0–1)
Arteriole thrombosis3.43.41.62.0
Immunofluorescence of glomerulus
  IgM2 (1–2)2 (1–3)2 (1–2)2 (1–2)
  IgG1 (0–2)1 (0–2)1 (0–2)1 (0–1)
  IgA2 (1–3)2 (1–3)2 (1–3)2 (0.5–2.5)b
  C33 (2–3)3 (3–4)3 (3–3)3 (3–3)
  C41 (0–2)1 (0–2)1 (0–2)1 (0–2)
  C1q2 (1–3)3 (2–3)a2 (1.75–3)b2 (1–3)b
  • a p < 0.05 compared with NC group.

  • b p < 0.05 compared with SC group.

  • c p < 0.05 compared with C1 group. IQR: interquartile range; ISN/RPS: International Society of Nephrology/Renal Pathology Society; IgM: immunoglobulin M; C3: complement factor 3; NC: noncrescent group; SC: segmental crescent group.