Group A | Group B | Group C | p | ||||
---|---|---|---|---|---|---|---|
A vs B | A vs C | B vs C | |||||
Metabolic variables | |||||||
nv = 33 | MET | 4.4 (3.7–5.4) | 3.7 (3.0–4.4) | 3.6 (3.0–4.8) | ns | ns | ns |
nv = 33 | VO2 (peak) ml/kg | 71.5 (62.3–78.5) | 68 (54–78) | 57.0 (44.8–83.5) | ns | ns | ns |
Ventilatory variables | |||||||
nv = 28 | VE/VCO2 (VeT), %predicted | 40.2 (31.7–44.5) | 39.6 (33.4–45.3) | 41.0 (35.0–46.0) | ns | ns | ns |
nv = 33 | Vd/Vt (peak) %predicted | 108.5 (77.43–152.0) | 127.4 (94.7–163.3) | 166.2 (99.5–228.0) | ns | ns | ns |
Cardiovascular variables | |||||||
nv = 33 | ΔHR/ΔVO2, % | 73.6 (57.2–91.1) | 87.5 (66.1–102.0) | 63.1 (57.2–99.3) | ns | ns | ns |
nv = 33 | VO2/HR (peak), %predicted | 92.5 (80.5–107.8) | 80.0 (60.0–103.0) | 75.0 (58.0–91.8) | ns | ns | ns |
Gas exchange variables | |||||||
nv = 33 | P(Ai-a)O2 (peak)*, %predicted | 101.0 (66.0–125.5) | 127.0 (98.0–262.0) | 250.5 (188.8–323.8) | 0.6621 | 0.0177 | 0.0684 |
nv = 28 | PetCO2 (VeT), mmHg | 35.0 (29.0–38.5) | 38.5 (33.4–42.8) | 32.0 (28.9–35.8) | ns | ns | ns |
nv = 33 | Resting DLCO**,%predicted | 68.0 (56.5–82.3) | 64.0 (37.0–73.0) | 44.0 (25.0–53.0) | 0.7625 | 0.0498 | 0.2140 |
↵* P value for the Kruskal-Wallis test: 0.0120.
↵** P value for the Kruskal-Wallis test: 0.0478. CPET: cardiopulmonary exercise test; PML: peripheral/muscular limitation; MET: metabolic equivalent of task; VeT: ventilatory threshold; VO2 (peak): oxygen uptake at peak exercise; HR: heart rate; ΔHR/ΔVO2: (HRpeak − HRrest) to (VO2peak − VO2rest) ratio; VE/VCO2 (VeT): ventilatory equivalent for CO2 at VeT; Vd/Vt (peak): physiological dead space/tidal volume ratio at peak exercise; P(Ai-a)O2 (peak): alveolar-arterial gradient at peak exercise; PetCO2 (VeT): end tidal CO2 pressure at VeT; nv: no. values; ns: non-significant; %predicted: percent of predicted value; IQR: interquartile range.