Characteristics of patients with RA and non-RA comparator subjects diagnosed with OSA after RA incidence/index date. Values are mean ± SD (n) unless otherwise specified.
| Characteristic | RA, n = 97 | Non-RA, n = 80 | p |
|---|---|---|---|
| Age at OSA diagnosis, yrs | 64.4 ± 11.4 | 64.9 ± 10.8 | 0.79 |
| Female, n (%) | 59 (61) | 45 (56) | 0.54 |
| AHI | 27.0 ± 23.0 (92) | 26.4 ± 25.9 (77) | 0.56 |
| RDI | 39.7 ± 29.7 (86) | 40.4 ± 25.4 (77) | 0.52 |
| ESS | 9.3 ± 5.2 (81) | 8.0 ± 4.8 (66) | 0.14 |
| CRP, mg/l | 7.3 ± 17.3 (51) | 2.4 ± 2.4 (11) | 0.47 |
| ESR, mm/h | 20.4 ± 18.3 (69) | 15.3 ± 15.7 (26) | 0.12 |
| Blood neutrophils | 5.3 ± 2.6 (82) | 4.5 ± 1.9 (62) | 0.035 |
| Blood lymphocytes | 1.6 ± 0.6 (84) | 1.7 ± 0.7 (63) | 0.14 |
| Neutrophil/lymphocyte ratio | 4.3 ± 3.4 (82) | 3.3 ± 3.3 (62) | 0.011 |
| BMI at OSA diagnosis, kg/m2 | 34.2 ± 8.4 (97) | 33.6 ± 7.0 (80) | 0.74 |
| BMI ≥ 30 kg/m2 at OSA diagnosis, n (%) | 69 (71) | 53 (66) | 0.48 |
| Statin use, n (%) | 23 (24) | 27 (34) | 0.14 |
| Glucocorticoid use, n (%) | 35 (36) | 3 (4) | |
| Biologic use, n (%) | 12 (12) | 0 (0) | |
| OSA machine prescription, n (%) | 78 (80) | 67 (84) | 0.50 |
| CPAP | 57 | 56 | |
| BiPAP | 8 | 2 | |
| APAP | 0 | 2 | |
| ASV | 4 | 0 | |
| Oral appliance | 0 | 1 | |
| Followup machine compliance, % | 80 ± 30 (62) | 80 ± 20 (53) | 0.51 |
| Followup AHI | 4.2 ± 5.2 (25) | 7.9 ± 9.8 (25) | 0.34 |
| Followup ESS | 6.2 ± 3.6 (51) | 6.7 ± 4.6 (47) | 0.84 |
| Oxygen use, n (%) | 9 (9) | 4 (5) | 0.28 |
RA: rheumatoid arthritis; OSA: obstructive sleep apnea; AHI: Apnea/hypoapnea Index; RDI: Respiratory Disturbance Index; ESS: Epworth Sleepiness Scale; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; BMI: body mass index; CPAP: continuous positive airway pressure; BiPAP: bilevel positive airway pressure; APAP: automatic titrating positive airway pressure; ASV: adaptive servo-ventilation.