Table 5.

Comparison of the most important clinical and laboratory measures between the 2 groups, divided based on the physician’s global assessment (PGA) score cutoff value.

FeatureInactive or Mildly Active DiseaseModerately or Severely Active Disease
Mean PGA of disease activity ± 2 SD0.33 (± 0.85)4.83 (± 3.64)
Arthritis
  No. patients with ≥ 2 joints with active arthritis on physical examination3/31 (9.68%)25/26 (96.15%)
  Mean no. joints with active arthritis ± 2 SD0.48 (± 2.24)13.96 (± 33.33)
No. patients with sJIA rash for ≥ 1 day by parental history in preceding 2 weeks or on physical examination2/31 (6.45%)5/26 (19.23%)
No. patients with fever > 38°C for ≥ 2 days in the preceding 2 weeks1/30 (3.33%)2/26 (7.69%)
Patient’s global assessment of disease activity
  No. patients with score > 0.4 cm9/30 (30.00%)20/26 (76.92%)
  Mean score ± 2 SD0.94 (± 3.54)2.75 (± 4.71)
Parent’s global assessment of disease activity
  No. patients with score > 0.9 cm7/31 (22.58%)18/25 (72.00%)
  Mean score ± 2 SD1.14 (± 4.78)3.84 (± 6.49)
CRP
  No. patients with CRP > 5.5 mg/l5/30 (16.67%)15/25 (60.00%)
  Mean CRP ± 2 SDN/A*N/A*
ESR
  No. patients with ESR > 23 mm/h3/29 (10.34%)13/25 (52.00%)
  Mean ESR ± 2 SD10.59 (± 18.49)32.68 (± 64.16)
Hemoglobin
  No. patients with hemoglobin < 119 g/l3/31 (9.68%)15/26 (57.69%)
  Mean hemoglobin ± 2 SD128.94 (± 20.80)118 (± 32.57)
  • * Not available. Mean CRP could not be calculated because some laboratories reported values above or below a certain threshold rather than absolute values. sJIA: systemic juvenile idiopathic arthritis; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.