Table 1.

Baseline characteristics of patients.

Variablesn = 27
Center, Nice/Lille18/9
Sex, female/male24/3
Age, yrs, median (range)59 (38–81)
BMI, kg/m2, median (IQR)25 (22–28)
History of smoking9
NYHA score
  Class I3
  Class II13
  Class III8
  Class IV3
lcSSc/dcSSc22/5
Overlap syndromes5
Antibodies
  Anticentromere9
  Antitopoisomerase I11
  Other10
Disease ≥ 5 yrs16
Modified Rodnan score, median (IQR)4.5 (2.0–12)
Raynaud phenomenon26
Digital ulcers14
Telangiectasia16
Articular expression of the disease6
Gastroesophageal reflux disease17
Arterial hypertension7
History of SSc renal crisis0
Preexisting signs of right heart disease3
ECG conduction blocks8
Dry cough8
Hemoglobin, g/dl (IQR)12.40 (12.08–13.73)
Creatinine, µmol/l (IQR)71 (61–82)
BNP < 50 ng/l or NT-proBNP < 300 ng/l15
BNP 50–300 ng/l or NT-proBNP 300–1400 ng/l8
BNP > 300 ng/l or NT-proBNP > 1400 ng/l0
  • BMI: body mass index; IQR: interquartile range; NYHA: New York Heart Association; SSc: systemic sclerosis; lcSSc: limited cutaneous SSc; dcSSc: diffuse cutaneous SSc; BNP: brain natriuretic peptide; ECG: electrocardiograph; NT-proBNP: N terminal proBNP.