Clinical and laboratory characteristics of patients with recurrent AAU and healthy controls. Values are n (%) unless otherwise specified.
| Variables | Group 1, AxSpA, n = 20 | Group 2, NSBP, n = 6 | Group 3, Asymptomatic, n = 24 | Group 4, Controls, n = 21 | Group 5, AS, n = 30 | p |
|---|---|---|---|---|---|---|
| Female | 13 (75) | 0 (0) | 12 (50) | 14 (66.7) | 6 (20) | 0.921* |
| White | 11 (55) | 3 (50) | 14 (58.3) | 12 (57.1) | — | 1.000* |
| Age, yrs, mean ± SD | 44.8 ± 14.3 | 44.5 ± 11.2 | 42.3 ± 11.8 | 47.1 ± 12 | 40.40 ± 11 | 0.378Δ |
| Age at onset of uveitis, yrs, mean ± SD | 38.9 ± 14 | 35.5 ± 14.8 | 36.8 ± 12.8 | NA | NA | 0.817Δ |
| Eye disease duration, yr, mean ± SD | 6.2 ± 6.1 | 7.2 ± 6.2 | 5.5 ± 6.4 | NA | NA | 0.491¶ |
| Active uveitis | 7 (35) | 2 (33.3) | 14 (58.3) | NA | NA | 0.252* |
| Age at onset of back pain, yrs, mean ± SD | 31.2 ± 10 | 30.5 ± 11.3 | NA | NA | NA | 0.893€ |
| Back pain duration, yrs, mean ± SD | 13.8 ± 10.5 | 14.8 ± 14.3 | NA | NA | 17 ± 11.52 | 0.629Δ |
| Inflammatory back pain (expert opinion/ASAS definition) | 9 (45) | NA | NA | NA | 30 (100) | |
| Assessment instruments, mean ± SD | BASDAI 4.2 ± 2.3 | NA | NA | NA | BASDAI 4.9 ± 2.6, | 0.356€ |
| BASFI 2.9 ± 2.7 | BASFI 3.7 ± 2.8 | 0.296€ | ||||
| BASMI 3.0 ± 1.2 | — | |||||
| ASDAS-ESR 3.1 ± 1.1 | — | 0.059€ | ||||
| ASDAS-CRP 3.1 ± 1.1 | ASDAS-CRP 3.8 ± 1.3 | |||||
| Enthesitis score (MASES) ≥ 2 | 6 (30) | 1 (16.7) | 1 (4.17) | 0 (0) | — | 0.007* |
| ESR, mm/1st h, mean ± SD | 23.7 ± 18 | 9.5 ± 6.2 | 26.4 ± 22.4 | NA | — | 0.176Δ |
| CRP, mg/l, mean ± SD | 7.7 ± 9.2 | 2.5 ± 2.3 | 4.3 ± 4.7 | NA | 10.9 ± 10.6 | 0.014¶ |
| HLA-B27+ | 12 (60) | 0 (0) | 12 (50) | NA | 26 (87) | 0.025* |
↵* Fisher’s exact test;
↵€ Student t test;
↵Δ ANOVA;
↵¶ Kruskal-Wallis test; NA: not applicable; —: data not available. AAU: acute anterior uveitis; axSpA: axial spondyloarthritis; NSBP: nonspecific back pain; AS: ankylosing spondylitis; ASAS: Assessment of Spondyloarthritis international Society; MASES: Maastricht Ankylosing Spondylitis Enthesitis Score; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; BASMI: Bath Ankylosing Spondylitis Metrology Index; ESR: erythrocyte sedimentation rate; ASDAS-ESR: Ankylosing Spondylitis Disease Activity Score-ESR; CRP: C-reactive protein.