Demographic data and clinical features of 411 patients with Takayasu arteritis. Values are n (%) unless otherwise specified.
| Characteristic | Total | Heart Involved Group | Control Group | p | Chi-square |
|---|---|---|---|---|---|
| Total, n | 411 | 164 | 247 | ||
| Sex | |||||
| Female | 325 (79.1) | 127 (77.4) | 198 (80.2) | 0.54 | 0.44 |
| Male | 86 (20.9) | 37 (22.6) | 49 (19.8) | ||
| Age at onset, yrs, median (IQR) | 23.0 (18.0–30.0) | 23.0 (17.3–30.0) | 23.0 (18.0–31.0) | 0.89 | |
| < 20 | 145 (35.3) | 56 (34.1) | 89 (36.0) | ||
| ≥ 20 to < 30 | 163 (39.7) | 68 (41.5) | 95 (38.5) | ||
| ≥ 30 to < 40 | 72 (17.5) | 25 (15.2) | 47 (19.0) | ||
| ≥ 40 | 31 (7.5) | 15 (9.1) | 16 (6.5) | ||
| Duration of disease at admission, mos, median (IQR) | 21.0 (6.0–60.0) | 24.0 (7.3–84.0) | 16.0 (4.0–48.0) | 0.001* | |
| < 60 | 325 (79.1) | 120 (73.2) | 205 (83.0) | ||
| ≥ 60 | 86 (20.9) | 44 (26.8) | 42 (17.0) | 0.016* | 5.75 |
| Disease activity while taking first echocardiogram test | |||||
| Active | 329 (80.0) | 133 (81.1) | 196 (79.4) | 0.67 | 0.19 |
| Stable | 82 (20.0) | 31 (18.9) | 51 (20.6) | ||
| Constitutional findings | |||||
| Fever | 128 (31.1) | 45 (27.4) | 83 (33.6) | 0.19 | 1.75 |
| Malaise | 122 (29.7) | 51 (31.1) | 71 (28.7) | 0.61 | 0.26 |
| Weight loss | 82 (20.0) | 41 (25.0) | 41 (16.6) | 0.037* | 4.36 |
| Symptoms | |||||
| Arthralgia | 37 (9.0) | 7 (4.3) | 30 (12.1) | 0.006* | 7.47 |
| Rash | 32 (7.8) | 11 (6.7) | 21 (8.5) | 0.51 | 0.44 |
| Vascular findings | |||||
| Vascular bruit | |||||
| Carotid arteries | 257 (62.5) | 109 (66.5) | 148 (59.9) | 0.18 | 1.80 |
| Subclavian arteries | 159 (38.7) | 74 (45.1) | 85 (34.4) | 0.029* | 4.77 |
| Abdominal | 114 (27.7) | 53 (32.3) | 61 (24.7) | 0.09 | 2.86 |
| Hypertension | 209 (50.9) | 94 (57.3) | 115 (46.6) | 0.033* | 4.56 |
| Ischemic stroke | 22 (5.4) | 5 (3.0) | 17 (6.9) | 0.09 | 2.86 |
| Renal dysfunction | 47 (11.4) | 28 (17.1) | 19 (7.7) | 0.003* | 8.56 |
| Laboratory findings | |||||
| Level of ESR, mm/h, median (IQR) | 26.0 (11.0–65.0) | 28.0 (11.0–69.0) | 26.0 (11.0–65.0) | 0.83 | |
| Level of CRP, mg/l, median (IQR) | 12.8 (3.4–44.8) | 16.3 (4.7–52.5) | 12.3 (3.2–43.8) | 0.23 | |
| Level of hs-CRP, mg/l, median (IQR) | 8.8 (2.0–12.5) | 10.0 (2.9–26.0) | 7.0 (1.8–10.0) | 0.017* | |
| Level of WBC, 109/l, median (IQR) | 8.2 (6.6–11.0) | 8.5 (6.7–11.4) | 8.0 (6.5–10.6) | 0.21 | |
| Numano angiographic classification | |||||
| Type I | 91 (22.1) | 25 (15.2) | 66 (26.7) | 0.006* | 7.53 |
| Type IIa | 16 (3.9) | 6 (3.7) | 10 (4.0) | 0.84 | 0.04 |
| Type IIb | 16 (3.9) | 8 (4.9) | 8 (3.2) | 0.40 | 0.71 |
| Type III | 12 (2.9) | 4 (2.4) | 8 (3.2) | 0.77** | 0.22 |
| Type IV | 26 (6.3) | 11 (6.7) | 15 (6.1) | 0.80 | 0.07 |
| Type V | 250 (60.8) | 110 (67.1) | 140 (56.7) | 0.028* | 4.82 |