Number of all-cause deaths and HR for all-cause death comparing patients with SLE to those without at 4 timepoints of the year-long followup.
| Time Since Stroke Onset | All-cause Death* | HR (95% CI) | ||
|---|---|---|---|---|
| SLE | Non-SLE | Model 1† | Model 2‡ | |
| Ischemic stroke | n = 363 | n = 1436 | ||
| 1 mo | 25 (7) | 115 (8) | 1.10 (0.71–1.72) | 0.85 (0.53–1.37) |
| 3 mos | 40 (11) | 152 (11) | 1.43 (1.00–2.05) | 1.11 (0.75–1.63) |
| 6 mos | 50 (14) | 178 (12) | 1.60 (1.16–2.22) | 1.21 (0.85–1.71) |
| 12 mos | 68 (19) | 215 (15) | 1.85 (1.39–2.45) | 1.41 (1.04–1.91) |
| Age < 65 yrs | 12/149 (8) | 12/304 (4) | 2.29 (0.99–5.30) | 1.92 (0.78–4.74) |
| Age ≥ 65 yrs | 56/202 (26) | 203/1132 (18) | 1.77 (1.31–2.40) | 1.35 (0.97–1.87) |
| Hemorrhagic stroke | n = 60 | n = 216 | ||
| 1 mo | 18 (30) | 41 (19) | 2.37 (1.32–4.24) | 1.73 (0.87–3.42) |
| 3 mos | 24 (40) | 45 (21) | 2.67 (1.57–4.54) | 2.01 (1.08–3.75) |
| 6 mos | 25 (42) | 49 (23) | 2.53 (1.50–4.26) | 1.94 (1.05–3.57) |
| 12 mos | 25 (42) | 56 (26) | 2.30 (1.38–3.82) | 1.74 (0.95–3.17) |
| Age < 65 yrs | 11/29 (38) | 6/47 (13) | 5.79 (1.60–20.86) | 6.00 (1.23–29.10) |
| Age ≥ 65 yrs | 14/31 (45) | 50/169 (30) | 1.84 (0.98–3.43) | 1.67 (0.81–3.45) |
↵* Data are n (%), or n/total in category (%) for age stratifications.
↵† Adjusted for age at stroke onset, sex, region of residence, country of birth, education, and calendar period (stroke onset during or after 2006).
↵‡ Further adjusted for history of congestive heart disease, hypertension, diabetes, atrial fibrillation, chronic kidney disease, and infection frailty at stroke onset. SLE: systemic lupus erythematosus.