Associations between baseline knee structural abnormalities and change in effusion-synovitis over 24 months. Dependent variable: an increase in effusion-synovitis over 24 months. Independent variable: baseline knee structures.
| Knee Structures | Volume Change#, RR (95% CI) | Score Change*, OR (95% CI) |
|---|---|---|
| Bone marrow lesion, 0–3 | ||
| Total | 1.31 (1.14–1.49) | 1.03 (0.84–1.25) |
| Tibiofemoral | 1.30 (1.15–1.48) | 1.01 (0.83–1.22) |
| Patellar | 1.04 (0.88–1.22) | 1.01 (0.79–1.29) |
| Cartilage defect, 0–4 | ||
| Total | 1.66 (1.15–2.40) | 1.43 (1.05–1.95) |
| Tibiofemoral | 1.38 (1.13–1.69) | 1.16 (0.91–1.46) |
| Patellar | 1.01 (0.88–1.15) | 1.18 (0.98–1.43) |
| Cartilage volume, ml | ||
| Total | 0.90 (0.79–1.03) | 0.84 (0.70–1.00) |
| Tibial | 0.87 (0.72–1.05) | 0.83 (0.64–1.08) |
| Patellar | 0.92 (0.75, 1.14) | 0.80 (0.59–1.07) |
| Osteophyte, 0–3 | ||
| Total | 1.40 (1.18–1.66) | 1.04 (0.82–1.32) |
| Tibiofemoral | 1.44 (1.23–1.70) | 1.06 (0.83–1.36) |
| Patellar | 1.31 (1.12–1.53) | 1.05 (0.82–1.34) |
| Joint space narrowing, 0–3 | ||
| Total | 1.55 (1.26–1.91) | 1.40 (1.05–1.85) |
| Tibiofemoral | 1.80 (1.42–2.28) | 1.56 (1.11–2.20) |
| Patellofemoral | 1.18 (1.00–1.38) | 1.21 (0.95–1.53) |
↵Generalized binary# and ordinal* logistic regression models were used, after adjustment for age, sex, body mass index, site, and intervention.
↵# Effusion-synovitis volume change was dichotomized using least significant change criterion. Statistically significant differences at α = 0.05 are in bold face.