Baseline characteristics and healthcare use of the patients with L-TGCT and D-TGCT, Denmark, 1997–2012, ascertained starting January 1, 1994, and up to 36 months before and including the index date. Values are n (%) unless otherwise specified.
| Characteristics | L-TGCT, n = 2087 | D-TGCT, n = 574 |
|---|---|---|
| Sex | ||
| Women | 1274 (61.0) | 295 (51.4) |
| Men | 813 (39.0) | 279 (48.6) |
| Age at index date, yrs | ||
| 18–19 | 23 (1.1) | 13 (2.3) |
| 20–39 | 720 (34.5) | 187 (32.6) |
| 40–59 | 883 (42.3) | 231 (40.2) |
| 60–79 | 436 (20.9) | 122 (21.3) |
| ≥ 80 | 25 (1.2) | 21 (3.7) |
| Age at index date, yrs, median (range) | 47.0 (18.0–91.0) | 47.0 (18.0–91.0) |
| Calendar yr of diagnosis | ||
| 1997 | 106 (5.1) | 26 (4.5) |
| 1998 | 95 (4.6) | 24 (4.2) |
| 1999 | 94 (4.5) | 32 (5.6) |
| 2000 | 118 (5.7) | 50 (8.7) |
| 2001 | 123 (5.9) | 33 (5.7) |
| 2002 | 141 (6.8) | 41 (7.1) |
| 2003 | 133 (6.4) | 49 (8.5) |
| 2004 | 131 (6.3) | 43 (7.5) |
| 2005 | 169 (8.1) | 32 (5.6) |
| 2006 | 134 (6.4) | 23 (4.0) |
| 2007 | 121 (5.8) | 36 (6.3) |
| 2008 | 93 (4.5) | 37 (6.4) |
| 2009 | 154 (7.4) | 42 (7.3) |
| 2010 | 149 (7.1) | 49 (8.5) |
| 2011 | 138 (6.6) | 29 (5.1) |
| 2012 | 188 (9.0) | 28 (4.9) |
| History of treatments and diagnostic procedures | ||
| Any operation or surgery of musculoskeletal system | 750 (35.9) | 291 (50.7) |
| MRI/CT scan | 316 (15.1) | 169 (29.4) |
| History of musculoskeletal injuries | ||
| Any injury to spine or limbs | 202 (9.7) | 98 (17.1) |
| Any fracture | 65 (3.1) | 25 (4.4) |
| Fracture of sternum, spine, or pelvis | 4 (0.2) | 4 (0.7) |
| Fracture of upper limb | 42 (2.0) | 16 (2.8) |
| Fracture of lower limb | 22 (1.1) | 5 (0.9) |
| History of chronic diseases | 349 (16.7) | 296 (51.6) |
| Osteoarthritis | ||
| Any arthropathy | 136 (6.5) | 143 (24.9) |
| Chronic renal impairment | 0 (0.0) | 0 (0.0) |
| Chronic lung disease | 24 (1.1) | 10 (1.7) |
| Cardiovascular disease | 77 (3.7) | 29 (5.1) |
| History of use of other prescription medications, since 2004 | ||
| Analgesics | 298 (14.3) | 103 (17.9) |
| Corticosteroids for systemic use | 123 (5.9) | 53 (9.2) |
| Antibiotics | 728 (34.9) | 183 (31.9) |
| Antiinflammatory and antirheumatic agents | 571 (27.4) | 214 (37.3) |
| Muscle relaxants | 7 (0.3) | 0 (0.0) |
| Chemotherapy | 9 (0.4) | 5 (0.9) |
| History of healthcare use | ||
| At least 1 inpatient hospitalization | 739 (35.4) | 305 (53.1) |
| No. hospitalizations, median (range) | 1 (1–12) | 1 (1–16) |
| At least 1 outpatient hospital visit | 1672 (80.1) | 531 (92.5) |
| No. outpatient visits, median (range) | 3 (1–27) | 4 (1–20) |
| At least 1 emergency room visit | 672 (32.2) | 240 (41.8) |
| No. emergency room visits, median (range) | 1 (1–11) | 1 (1–8) |
| At least 1 outpatient prescription dispensation, since 2004 | 1141 (54.7) | 298 (51.9) |
| No. different classes of dispensed outpatient prescriptions, median (range) | 3 (1–11) | 3 (1–11) |
L-TGCT: localized tenosynovial giant cell tumor; D-TGCT: diffuse tenosynovial giant cell tumor; MRI: magnetic resonance imaging; CT: computer tomography.