The percentage of RA incident cases and controls with selected comorbidities.
| Variables | Any Encounter | Maclean, et al11 | MacLean/Lacaille5 | Shipton, et al12 | Rheumatologist | Hospital | Combination |
|---|---|---|---|---|---|---|---|
| Cases, n | 27,694 | 13,344 | 4726 | 12,280 | 9976 | 3497 | 15,976 |
| Age, yrs, mean | 55.5 | 56.5 | 55.3 | 56.5 | 54.3 | 65.0 | 55.8 |
| Female, % | 67.8 | 70.4 | 71.3 | 70.2 | 70.1 | 70.3 | 69.4 |
| Comorbidity, % | |||||||
| Cancer | 34.7 | 35.2 | 21.2 | 35.3 | 34.4 | 43.8 | 35.0 |
| CHD | 30.3 | 30.2 | 18.0 | 30.3 | 29.1 | 43.0 | 30.4 |
| CVD | 79.0 | 80.1 | 71.5 | 80.2 | 78.4 | 88.0 | 79.4 |
| Diabetes | 24.8 | 24.1 | 19.4 | 24.1 | 23.6 | 27.2 | 24.6 |
| Infection | 84.0 | 84.8 | 78.4 | 84.7 | 84.2 | 86.3 | 84.0 |
| Lymphoma | 3.8 | 4.3 | 2.2 | 4.4 | 4.4 | 6.7 | 4.3 |
| Mental health | 73.4 | 71.7 | 68.9 | 71.4 | 72.3 | 68.4 | 71.9 |
| Renal | 11.6 | 12.0 | 6.2 | 12.1 | 11.1 | 18.0 | 12.1 |
| Controls, n | 109,598 | 52,562 | 18,729 | 48,356 | 39,491 | 13,550 | 63,023 |
| Comorbidity, % | |||||||
| Cancer | 27.0 | 27.6 | 24.0 | 27.7 | 26.6 | 33.7 | 27.4 |
| CHD | 22.1 | 22.4 | 18.6 | 22.4 | 20.5 | 29.7 | 22.1 |
| CVD | 64.9 | 65.7 | 61.2 | 65.8 | 64.1 | 75.9 | 65.3 |
| Diabetes | 19.4 | 19.7 | 17.6 | 19.9 | 19.1 | 24.1 | 19.6 |
| Infection | 64.5 | 64.5 | 63.4 | 64.4 | 63.4 | 67.3 | 64.3 |
| Lymphoma | 2.2 | 2.2 | 1.7 | 2.1 | 2.0 | 2.6 | 2.1 |
| Mental health | 58.7 | 58.7 | 58.9 | 58.8 | 59.1 | 60.7 | 58.8 |
| Renal | 7.2 | 7.3 | 5.8 | 7.4 | 6.6 | 10.3 | 7.2 |
RA: rheumatoid arthritis; cancer: all malignancies except lymphoma; CHD: coronary heart disease; CVD: cardiovascular disease excluding CHD.