Patient Characteristics | Values |
---|---|
Baseline age, yrs | 32.3 ± 8.3 |
Male | 142 (55.7) |
Postsecondary education | 180 (70.6) |
Married | 162 (63.5) |
Academic or executive-level occupation | 76 (29.8) |
Peripheral arthritis | 118 (46.3) |
Baseline disease duration | 1.5 ± 0.9 |
Baseline sacroiliitis or spinal inflammation on radiograph, CT, or MRI | 153 (60.0) |
Baseline CRP | 6.7 ± 9.6 |
Baseline HLA-B27–positive | 230 (90.2) |
No comorbidities at baseline | 203 (79.6) |
Mean BASDAI pre-index | 3.3 ± 1.8 |
Mean BASFI pre-index | 1.8 ± 1.7 |
Baseline physician’s assessment of disease activity | 2.9 ± 1.9 |
Nonadherent on physiotherapy recommendations | 127 (49.8) |
Nonadherent on nonbiologic drug recommendations | 16 (6.3) |
Nonadherent on specialist care for uveitis | 0 (0) |
Nonadherent on specialist care for psoriasis | 9 (3.5) |
Nonadherent on specialist care for IBD | 2 (0.8) |
Positive response to anti-TNF therapy | NA |
Time on anti-TNF, mos, 1 yr from index | NA |
QALY | 0.674 ± 0.156 |
Total costs (2013 euros) | 1108 ± 1848 |
Nonbiologic costs (2013 euros) | 1108 ± 1848 |
Nonbiologic HR costs | 898 ± 1391 |
Work productivity costs | 214 ± 1070 |
CT: computed tomography; MRI: magnetic resonance imaging; CRP: C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; anti-TNF: antitumor necrosis factor; QALY: quality-adjusted life-years; HR: health resource; NA: not applicable.