Time | Hb, mg/dl | WBC, per cm2 | Platelet Count, k/cm2 | Serum Creatinine, mg/dl | UPCR, mg/mg | C3, 88–201 mg/dl | C4, 16–47 mg/dl | dsDNA Titer |
---|---|---|---|---|---|---|---|---|
3 mos before belimumab | 11.9 | 8.2 | 215 | 1.12 | 0.11 | 62 | 8 | 1:80 |
At initiation of belimumab | 11.8 | 4.0 | 176 | 0.89 | 0.1 | 73 | 17 | 1:40 |
6 mos after belimumab | 11.8 | 2.6 | 170 | 0.77 | 0.14 | 73 | 22 | — |
12 mos after belimumab | 12 | 2.1 | 140 | 0.83 | 0.25 | 59 | 16 | — |
First trimester, first pregnancy | 11.7 | 1.9 | 161 | 0.59 | 0.14 | 87 | 24 | 1:40 |
Second trimester, first pregnancy | 10.8 | 1.5 | 164 | 0.78 | 0.28 | 98 | 35 | 1:80 |
Third trimester, first pregnancy | 10.9 | 2.4 | 158 | 0.70 | 0.19 | 99 | 32 | 1:40 |
Postpartum, first pregnancy | 11.9 | 0.9 | 195 | 0.78 | — | 73 | 22 | 1:80 |
3 mos before second pregnancy | 12.1 | 1.37 | 274 | 0.79 | 0.12 | 122 | 36 | 1:80 |
First trimester, ∼8 weeks | 13.0 | 1.58 | 246 | 0.78 | — | — | — | — |
Second trimester, ∼20 weeks | 10.7 | 1.84 | 205 | 0.64 | 0.15 | 140 | 46 | — |
Third trimester, ∼34 weeks | 12.0 | 1.46 | 175 | 0.73 | 0.16 | — | — | — |
3 weeks postpartum, first belimumab infusion postpartum | 12.5 | 1.74 | 301 | 0.75 | 0.16 | — | — | — |
6 mos postpartum | 12.4 | 0.97 | 213 | 0.68 | 0.22 | 140 | 30 | 48 (quantitative) |
12 mos postpartum | 12.9 | 1.15 | 203 | 0.72 | — | — | — | — |
Hb: hemoglobin; WBC: white blood cell; UPCR: urine protein creatinine ratio.