Characteristics | Total Patients, n = 1274 | Employed Patients, n = 451 | ||||
---|---|---|---|---|---|---|
Activity Impairment | Absenteeism | Presenteeism | ||||
Estimate (95% CI) | p | Estimate (95% CI) | p | Estimate (95% CI) | p | |
Age, yrs | 0.01 (−0.06 to 0.08) | 0.83 | 0.00 (−0.08 to 0.08) | 0.99 | −0.14 (−0.27 to −0.02) | 0.02 |
Female | 3.69 (1.06−6.33) | < 0.01* | −0.36 (−2.65 to 1.93) | 0.76 | 2.03 (−1.76 to 5.81) | 0.29 |
RA disease duration | 0.87 (−0.62 to 2.35) | 0.25 | −0.15 (−1.56 to 1.25) | 0.76 | −0.01 (−2.30 to 2.28) | 0.99 |
Comorbidities positivity | 0.77 (−1.39 to 2.94) | 0.48 | 1.65 (−4.02 to 0.72) | 0.17 | 2.08 (−1.82 to 5.97) | 0.30 |
Pain VAS | 0.41 (0.35−0.47) | < 0.01* | −0.03 (−0.10 to 0.03) | 0.34 | 0.22 (0.12−0.33) | < 0.01* |
DAS28 remission | −2.97 (−5.13 to −0.81) | < 0.01* | −1.27 (−3.49 to 0.96) | 0.26 | −4.20 (−7.87 to −0.54) | 0.03* |
EQ-5D | −58.71 (−65.15 to −52.27) | < 0.01* | −11.98 (−18.28 to −5.68) | < 0.01* | −54.79 (−65.08 to −44.50) | < 0.01* |
Medication use | ||||||
Methotrexate | 0.46 (−1.58 to 2.50) | 0.66 | 1.58 (−0.59 to 3.84) | 0.15 | 4.06 (0.51–7.62) | 0.03* |
Other csDMARD | 1.38 (−1.13 to 3.89) | 0.28 | 0.15 (−2.61 to 2.90) | 0.92 | 2.95 (−1.53 to 7.43) | 0.20 |
Biologic agents | 3.57 (1.60–5.54) | < 0.01* | 0.23 (−1.71 to 2.16) | 0.82 | 2.13 (−1.04 to 5.30) | 0.19 |
Oral corticosteroid | 5.71 (3.10–8.32) | < 0.01* | −1.09 (−4.13 to 1.96) | 0.48 | 3.34 (−1.58 to 8.25) | 0.18 |
↵* p < 0.05. RA: rheumatoid arthritis; VAS: visual analog scale; DAS28: Disease Activity Score in 28 joints; csDMARD: conventional synthetic disease-modifying antirheumatic drugs.