Neutropenia and related variables according to IV bDMARD analyzed. Values are n unless otherwise specified.
| Variables | Abatacept | Infliximab | Tocilizumab | p* |
|---|---|---|---|---|
| Neutropenia, n (%)** | 5 (3.8) | 6 (2.8) | 41 (18.6) | < 0.001 |
| Grade 1 | 1 | 0 | 4 | |
| Grade 2 | 4 | 3 | 33 | |
| Grade 3 | 2 | 4 | ||
| Grade 4 | ||||
| Time to first episode of neutropenia, weeks, mean (range) | 9.3 (3–11.5) | 13.2 (2.2–18) | 15.2 (1–108) | 0.65 |
| History of neutropenia, n (%) | 4 (75) | 3 (50) | 3 (7.3) | < 0.001 |
| sDMARD | 3 (MTX) | 2 (MTX) | 1 (MTX) | |
| Biologic drug | 1 (ADA) | 2 (1 ADA/1 ETN) | ||
| Hematologic disorder | 1 (Felty) | |||
| Other cytopenias, n (%) | 1 (20) | 1 (16.6) | 9 (21.9) | 0.96 |
| Thrombocytopenia | 1 | 3 (2 with lymphopenia) | ||
| Lymphopenia | 6 | |||
| Pancytopenia | 1 |