Table 4.

Endocrine comorbidities in patients with PsA treated with DMARD compared with patients with PsA not treated with DMARD*. Values are n (%) unless otherwise specified.

ComorbiditiesPsA Not Treated with DMARD, n = 665PsA Treated with DMARD, n = 2496OR95% CI
Diabetes mellitus194 (29.2)687 (27.5)0.90.8–1.1
Hypothyroidism80 (12.0)32 (12.9)1.10.8–1.4
Hyperthyroidism6 (0.9)40 (1.6)1.80.8–4.2
Hyperparathyroidism4 (0.6)20 (0.8)1.30.5–3.9
Hyperprolactinemia0 (0)2 (0.1)1.01.0–1.0
Cushing disease1 (0.2)8 (0.3)2.10.3–17.1
Diabetes insipidus1 (0.2)2 (0.1)0.50.1–5.9
Addison disease0 (0)4 (0.2)1.01.0–1.0
Osteoporosis70 (10.5)346 (13.9)1.41.0–1.8
  • * Nonbiological DMARD: hydroxychloroquine, sulfasalazine, methotrexate, azathioprine, leflunomide, and cyclosporine; and biological DMARD: adalimumab, etanercept, infliximab, and golimumab. PsA: psoriatic arthritis; DMARD: disease-modifying antirheumatic drug.