Table 4.

The effect of muscle, lung, and cardiac dysfunction on the 6MWT and TUG test in patients with JDM (n = 59), a linear, multivariable regression analysis.

Variable	Univariable Analysis			Multivariable Analysis
Variable	β	95% CI	p	β	95% CI	p
6MWT
Sex	34.81	−8.14 to 77.77	0.110	6.46	−26.51 to −39.44	0.695
Age, yrs	−1.03	−2.73 to 0.683	0.234	−1.13	−2.70 to 0.45	0.156
Weight	−0.09	−1.17 to 0.981	0.862	−2.16	−3.44 to −0.87	0.001^**
Height	1.56	0.18–2.93	0.028^*	3.85	2.11–5.59	< 0.001^***
CMAS	8.23	4.88–11.58	< 0.001^***	6.39	3.57–9.21	< 0.001^***
Low DLCOc	−43.98	−85.21 to −2.74	0.037^*	−38.91	−70.06 to −7.77	0.007^**
HRCT findings	−55.29	−97.99 to −12.60	0.012^*	−40.92	−71.63 to −10.20	0.040^*
MRI findings	−42.45	−85.98 to 1.09	0.056
Low FVC	−63.84	−118.36 to −9.31	0.023^*
Diastolic BP	−1.48	−3.07 to 0.11	0.067
TUG
Sex	−0.27	−1.41 to 0.876	0.640	−0.14	−0.99–0.71	0.736
Age, yrs	0.05	0.00–0.09	0.032	0.04	0.01–0.07	0.025^*
CMAS	−0.23	−0.32 to −0.15	< 0.001^***	−0.21	−0.28 to −0.13	< 0.001^***
Low FVC	2.13	0.75–3.51	0.003^**	1.94	0.85–3.03	0.001^**
MRI findings	1.26	0.14–2.39	0.029^*
HRCT findings	1.79	0.72–2.87	0.002^**
Systolic BP	0.02	−0.00 to 0.05	0.096
Diastolic BP	0.06	0.01–0.10	0.009^**

↵* p < 0.05.
↵** p < 0.01.
↵*** p < 0.001. 6MWT: 6-min walk test; TUG: timed up and go; JDM: juvenile dermatomyositis; CMAS: Childhood Myositis Assessment Score; low DLCOc: DLCO corrected by hemoglobin expressed as % of expected under the fifth percentile; HRCT: high-resolution computed tomography; MRI: magnetic resonance imaging; low FVC: forced vital capacity under the fifth percentile of predicted; BP: blood pressure.