Table 2.

Incidence of cardiovascular disease (CVD) outcomes among subjects with and without rheumatoid arthritis (RA) during followup time before/without and after fractures [any fragility or major osteoporotic (OP)^a fracture].

Outcome	Fracture Definition	CVD Rate per 100 Person-years
		RA Cohort		Non-RA Cohort
		No Fracture^b	After Fracture	No Fracture^b	After Fracture
Any CVD	Fragility	1.99	4.84	1.42	3.21
Any CVD	Major OP	2.04	5.79	1.50	3.36
IHD	Fragility	1.36	3.22	1.20	2.16
IHD	Major OP	1.44	3.50	1.24	2.25
HF	Fragility	1.28	3.37	0.82	2.06
HF	Major OP	1.32	4.03	0.87	2.24

↵a Major OP fracture defined as a fragility fracture at the hip, thoracic or lumbar spine, wrist, or shoulder.
↵b Person-years of followup and CVD events occurring before fracture are included in the “no fracture” computations. IHD: ischemic heart disease; HF: heart failure.