Association of heart rate and conduction times with disease activity at baseline in patients who did not use β-blockers (n = 455). All data are corrected for sex, age, symptom duration, RF or ACPA positivity, pain visual analog scale, and body mass index.
| DAS28 Levels | ESR Levels | CRP Levels | ||||
|---|---|---|---|---|---|---|
| B (CI) | p | B (CI) | p | B (CI) | p | |
| HR, bpm | 2.268 (1.222–3.331) | < 0.001 | 0.210 (0.151–0.268) | < 0.001 | 0.207 (0.152–0.261) | < 0.001 |
| QRS, ms | −1.078 (−2.217 to 0.060) | 0.063 | −0.038 (−0.105 to 0.028) | 0.259 | −0.028 (−0.091 to 0.036) | 0.392 |
| QT, ms | −4.207 (−6.994 to −1.420) | 0.003 | −0.372 (−0.531 to −0.213) | < 0.001 | −0.380 (−0.530 to −0.231) | < 0.001 |
| QTc, ms | 0.657 (−0.973 to 2.288) | 0.428 | 0.033 (−0.062 to 0.128) | 0.493 | −0.007 (−0.097 to 0.084) | 0.886 |
| PR, ms | −1.403 (−3.669 to 0.863) | 0.224 | −0.135 (−0.266 to 0.004) | 0.043 | −0.117 (−0.242 to 0.009) | 0.069 |
B: beta; CRP: C-reactive protein; DAS28: 28-joint Disease Activity Score; ESR: erythrocyte sedimentation rate; HR: heart rate; QTc: QT corrected for heart rate; RF: rheumatoid factor; ACPA: anticitrullinated protein antibodies.