Baseline characteristics of enrolled patients. Values are median (interquartile range) unless otherwise specified.
| Characteristics | Values |
|---|---|
| Age, yrs | 38.0 (31.0–47.0) |
| Disease onset age, yrs | 29.1 (20.4–38.1) |
| Female, n (%) | 469 (93.4) |
| Disease duration, yrs | 7.9 (3.7–14.0) |
| Education duration, yrs | 14.0 (12.0–16.0) |
| SBP, mmHg | 117.0 (110.0–127.0) |
| DBP, mmHg | 71.0 (65.0–79.0) |
| Height, cm | 160.0 (156.0–164.0) |
| Weight, kg | 55 (50.0–60.2) |
| BMI, kg/m2 | 21.4 (19.5–23.6) |
| Waist circumference, cm | 73.0 (67.0–81.0) |
| Hip circumference, cm | 90.0 (85.0–96.0) |
| Marital status, n (%) | |
| Single | 149 (29.7) |
| Married | 314 (62.5) |
| Divorced | 26 (5.2) |
| Bereaved | 13 (2.6) |
| Employment, n (%) | 235 (46.8) |
| Family history of rheumatic diseases, n (%) | 53 (10.6) |
| Alcohol consumption, n (%) | 142 (28.3) |
| Smoking status, n (%) | |
| Never | 447 (89.0) |
| Current | 36 (7.2) |
| Ex-smoker | 19 (3.8) |
| ESR, mm/h | 19.5 (10.0–32.0) |
| CRP, mg/dl | 0.09 (0.06–0.30) |
| Anti-dsDNA positivity, n (%) | 269 (53.7) |
| Complement 3, mg/dl | 79.2 (67.0–95.5) |
| Complement 4, mg/dl | 15.3 (10.4–20.4) |
| CH50, U/ml | 47.7 (37.0–56.7) |
| BDI | 7.0 (3.8–13.0) |
| SF-36 health survey | |
| PCS | 48.7 (42.6–53.8) |
| MCS | 49.6 (40.6–55.9) |
| PGA | 1.0 (0.5–1.0) |
| SLEDAI | 4.0 (2.0–6.0) |
| CCIa | 1.0 (1.0–2.0) |
| Charlson probability, 10-yr survival | 95.9 (90.1–95.9) |
| SDI ≥ 1, n (%) | 106 (21.1) |
| Medications, n (%) | |
| Hydroxychloroquine | 490 (97.6) |
| Methotrexate | 58 (11.6) |
| Corticosteroid | 480 (95.6) |
| Azathioprine | 154 (30.7) |
| Mycophenolate mofetil | 111 (22.1) |
| Tacrolimus | 49 (9.8) |
SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; BDI: Becker Depression Inventory; SF-36: Medical Outcomes Study Short Form-36; PCS: physical component score; MCS: mental component score; PGA: physician’s global assessment; SLEDAI: The Systemic Lupus Erythematosus Disease Activity Index; CCIa: age-adjusted Charlson Comorbidity Index; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.